Senior Scientist, Immunology & Immuno-oncology

ABOUT VALORA THERAPEUTICS INC.Valora Therapeutics Inc., based in San Diego, CA, is a pre-clinical stage biopharmaceutical company revolutionizing antibody therapeutics. Founded on the pioneering platform invented by Nobel Laureate Dr. Carolyn Bertozzi (Stanford), our proprietary chimeric antibody technology unlocks novel immune signaling mechanisms, driving transformative therapies in oncology, autoimmune diseases, and beyond.ABOUT THE OPPORTUNITYWe are seeking a highly motivated Senior Scientist to join our R&D Operations team and advance our next-generation antibody therapeutics. This lab-based role offers the chance to work at the cutting edge of antibody engineering, immunology and immune-oncology contributing to groundbreaking drug discovery.KEY RESPONSIBILITIESDesign and Execute Immunological AssaysDevelop and optimize advanced in vitro and ex vivo assays to evaluate antibody mechanisms, immune modulation, and effector cell engagement.Data Analysis and InterpretationAnalyze complex datasets using tools like GraphPad Prism, FlowJo, etc., and present findings to cross-functional teams.Innovate and HypothesizePropose novel immunological targets and mechanisms to expand Valora's R&D therapeutic development.Support Regulatory MilestonesContribute to IND-enabling studies and filings.CollaborateWork closely with interdisciplinary teams to drive project success.ABOUT YOUEducation and ExperiencePhD in Immunology, Molecular Biology, or related field with 3+ years of relevant post-doctoral experience, or MS with 6+ years of experience in a biopharmaceutical setting.· A proven track record of scientific productivity, including publications, patents, and presentations at scientific conferences in the areas of immunology and/or immuno-oncology.Technical SkillsImmunology: Advanced understanding of cellular and molecular immunology and Immuno-oncology, with expertise in methods to enhance innate and adaptive immunity in Immuno-oncology and reduce immune activity for autoimmunity. Advanced Flow CytometryExpertise in immune cell phenotyping and functional analysis.Primary Immune Cell SystemsDeep experience with human and mouse immune cell culture, co-culture in translational cellular systems.Immunological AssaysExpert-level proficiency in immunological assay design and execution with isolated primary human and mouse immune cells or PBMCs, including proficiency in cytotoxicity assays, cytokine detection (e.g., MSD, multiplex bead assays), and functional assays (ADCC, ADCP, CDC).Antibody EngineeringFamiliarity with Fc engineering, bispecific/multispecific antibodies, or related technologies.Data AnalysisStrong skills in statistical interpretation of scientific data.Experimental DesignAbility to design well-controlled experiments, including power analysis for sample size determination.Literature ReviewExperience with systematic reviews and critical evaluation of scientific literature.DocumentationExcellent record-keeping using electronic lab notebooks (ELNs) and adherence to data integrity standards.Personal QualitiesCritical ThinkerHypothesis-driven with creative problem-solving skills.Self-DrivenHighly self-motivated, taking personal accountability for outcomes and demonstrating pride in delivering excellence in execution.CommunicatorStrong written and verbal skills to present complex data clearly.CollaborativeThrives in cross-functional, fast-paced team environments.AdaptableQuick to learn new techniques and concepts.CommittedCommitted to scientific excellence and data integrity and committed for the success of the team and the company.PassionateDriven by scientific innovation and a desire to impact patients' lives.WHY JOIN VALORA?Pioneering ScienceBe at the forefront of antibody therapeutic development with a platform invented by a Nobel Laureate.Impactful WorkContribute to transformative therapies for oncology and immune diseases.Collaborative CultureJoin a dynamic, entrepreneurial team that values innovation and scientific excellence.Career GrowthProfessional development in a rapidly growing biotech.COMPENSATION AND BENEFITSCompetitive PackageIncludes salary, stock options, and performance-based bonuses.Comprehensive BenefitsMedical, dental, vision, 401(k), life insurance, flexible vacation, parental leave, flexible spending accounts, year-end shut down, and voluntary insurance coverage.Work EnvironmentFull-time, on-site role in our state-of-the-art San Diego laboratories (not remote).Annual Salary Range: $135,000-175,000JOIN USAt Valora Therapeutics, you'll harness the power of protein engineering to redefine medicine. Apply now to shape the future of biotherapeutics!Valora Therapeutics Inc. is an equal opportunity employer committed to diversity and inclusion.

Created: 2025-09-26