Senior Research Associate, Contractor

Siro Diagnostics, Inc. is seeking a talented, enthusiastic, and highly motivated Senior Research Associate, Assay Development contractor to join the R&D team and help in the development of isothermal amplification reaction based assays. This is a contract position that may be converted to a full-time position based upon business needs and company priorities. The ideal candidate will independently design and develop experiments covering all aspects of assay performance. An emphasis will be placed on new amplification chemistries, PCR primer design and NGS, etc. Candidates need to have hands-on lab experience with at least some preferably outside of an academic environment, good organizational skills, display a proactive attitude, and be flexible about their daily activities. The chosen candidate will thrive by being a self-starter with a proven track record of designing and running complex experiments with minimal supervision.Position Responsibilities:Independently execute and design novel nucleic acid amplification techniques including isothermal amplification and PCR/RT-PCR/ddPCROptimize multiplexing assays with Siro innovative molecular methods and technologiesTest and screen new primers to improve assay performance for detection of DNA and RNA analytesTest and screen new antibodies to improve assay performance, sensitivity and selectivity for detection of antigens and antibodies analytesDevelop nucleic acid detection and immunoassays, including initial development and feasibility activities, verification and validation studiesCreate NGS libraries from isolated DNA/RNA to further assay detection and discovery; Interpret NGS data and troubleshoot NGS method developmentConduct experiments with live pathogens and human clinical samples in a biosafety level 2 labExcellent organizational and documentation skills, able to multi-task, and efficient with hands-on laboratory researchTroubleshoot problems and identify solutions to technical challengesAnalyze and organize data, record and present results in a timely mannerAbility to work independently and follow instructions to execute and design experiments with little to no direct oversightAdditional duties as assignedDesired Skills:2 - 6 years of experience in a lab settingB.S. or M.S. degree in chemistry, biochemistry, molecular biology or a related discipline. No MD, PharmD, or DVM.Solid understanding of molecular biology techniques, assay development, antibody technologies, and relevant software and data analysis tools such as Microsoft Office, Google Suite, and JMP.Experience in common methods for DNA/RNA characterization such as PCR (endpoint, real-time, droplet)Experience in immunoassays and buffer formulationExperience in bacterial growth in an aseptic environmentExperience in assay optimization and troubleshooting. Excellent analytical thinking and problem-solving skills.Ability to work well with others in a collaborative environmentPhysical Requirements:Remaining in a stationary position, often standingor sitting for a prolonged periodof timeRepeating motionsthat may includethe wrists, handsand/or fingers

Created: 2025-09-26