(Sr.) Research Assistant - In Vivo Pharmacology

Aperture Therapeutics is advancing breakthrough therapeutics for age-related neurodegeneration, leveraging insights from human genetic diversity. We invite skilled scientists to join our mission-driven team to make a meaningful impact on patient lives.As a member of our Neuroinflammation research group, the (Senior) Research Assistant will play a crucial role in the pre-clinical evaluation of innovative therapies using rodent models. The ideal candidate will bring advanced technical expertise, a collaborative spirit, and a passion for translating science into therapies. We are committed to the ongoing professional growth of highly driven and independent scientists.Key Responsibilities:Conduct in vivo pharmacological studies using rodent models to support drug discovery and developmentPerform a wide range of compound administration techniques, including ICV, IT, IV dosingExecute tissue collection, dissection, and processing for subsequent histopathological and biochemical analysesApply proficiency in quantitative assays such as ELISA/MSD, qRT-PCR, and IHC to analyze experimental outcomesMaintain meticulous laboratory records and contribute to high standards of scientific rigor and data integrityCollaborate closely with cross-functional scientific teams, communicating results and contributing to research strategyQualifications:B.Sc. or M.Sc. in Cell Biology, Molecular Biology, Biochemistry, Neuroscience, or a related disciplineMinimum of three years' hands-on experience in rodent handling and colony managementDemonstrated expertise in various drug administration techniquesAdvanced skill in tissue dissection and preparation for diverse analytical assaysProficiency in quantitative biochemical techniquesHighly organized with exceptional critical thinking, troubleshooting, and communication abilitiesBenefits for Full-Time Employees:Competitive salary commensurate with experience and achievementsComprehensive benefits including medical, dental, vision, and life insuranceCommuter benefitsIf you are passionate about helping to advance the edge of innovation and developing impactful treatments for age-related diseases, we encourage you to apply and grow with us at Aperture Therapeutics.

Created: 2025-09-26