Principal, Scientific Statistical Programming

CSL's R&D organization is accelerating innovation to deliver greater impact for patients. With a project-led structure and a focus on collaboration, we’re building a future-ready team that thrives in dynamic biotech ecosystems. Joining CSL now means being part of an agile team committed to developing therapies that make a meaningful difference worldwide.Could you be our next Principal, Statistical Programmer? The job is in our King of Prussia, PA or Zurich Switzerland office. This is a hybrid position and is onsite three days a week.You will be a member of the Biostatistics team and plays a lead role in performing all statistical programming tasks required for clinical trial analysis and reporting. This position works closely with othermembers of the BDPM on various clinical projects. During clinical trial from start up to the end of the clinical data analysis/report, the incumbent will be responsible for planning, preparing, managing, coordinating and performingprogramming activities Is accountable oversee that applicable SEQ SOP and standards are implemented. Provide technical expertise for regulatory submission relevant to statistical programming deliverables. Support the functiondirector on managing and facilitating timelines and resource for the statistical programming group. This role has global responsibilities with potential for matrix management, and participation in global teams.Main Responsibilities:1. Provide statistical programming expertise in statistical programmingdeliverables, including data processing, CDISC compliance, regulatorysubmission and SAS coding.2. Help function director manage resources, timelines, and assignments for asingle or multiple clinical trials assigned to him/her. Estimate resourceneeds. Work closely with the function director on resource allocation,timeline consolidation and implementation.3. Oversee the work of statistical programming services provided by vendors toachieve quality, timely, and cost-effective study deliverables. Act as theprimary point of contact on all statistical programming matters with externalvendors that provide statistical programming services to Seqirus.4. Mentor junior programmers for their statistical programming activities.Provide technical support and mentoring to junior programmers.5. Support development and maintenance of the Seqirus statisticalprogramming relevant standards, SOPs/WI and guidance.6. Perform statistical programming on various tasks for clinical data analysisneeds, including but not limited to generating Study Data StandardizationPlan (SDSP), SDTM data/ADaM data specifications, CRF annotation forSDTM, define.xml, reviewers guide, system and study level macros, tables,listings and figures, regulatory e-submission components.7. As a SME, establish and implement programming standards and comply withregulatory requirements among project team members and across allstudies. Develop standard macros and/or tools for the statisticalprogramming platform for data analysis and reporting. Ensure that statisticalprograms developed for specific protocols are effectively portable to otherprotocols (Reusable code). Qualifications and Experience Requirements:Bachelor's Degree life science, computer programming, statistics etc.5+ years of experience in scientific programming/simulationsExpertise in R or Python, and knowledge of SASKnowledge of GIT, or similar version control systemExperience in working with larger data sets (>1m records)Ability to understand statistical issues, extract specifications, and convert into working simulation code#LI-HYBRIDAbout CSL BehringCSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor  visit and CSL Plasma at BenefitsFor more information on CSL benefits visit How CSL Supports Your Well-being | CSL. You Belong at CSLAt CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. To learn more about inclusion and belonging visit Opportunity EmployerCSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit

Created: 2026-02-08