Head of Oncology and Cell Therapy Genomics

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda''s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAre you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.Here, you will be a vital contributor to our inspiring, bold mission.Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.OBJECTIVESTakeda is committed to outsmarting cancer so that more patients may have access to our transformational medicines - a robust precision and translational medicine approach thoughtfully and strategically applied in drug development is of essential importance to achieve this important objective of our Oncology drug development organization. The Clinical Biomarker Sciences and Operations (CBSO) department at Takeda is seeking a strong scientific and strategic leader to head our clinical genomics efforts. The Head of Oncology and Cell Therapy Genomics is an exciting, new role within the growing Precision & Translational Medicine (PTM) function in the Takeda Oncology Therapeutic Area Unit (OTAU) reporting to the Head of Clinical Biomarker Sciences and Operations. The individual recruited for this new role will serve as the PTM resident genomic assay expert, whose role includes advising translational scientists on the best practices for implementing genomics-based biomarker assays/technologies into oncology Phase 1-3 clinical trials. The candidate will build an innovative, industry-leading oncology and cell therapy genomics function responsible for establishing and piloting innovative genomics technologies. They will identify and establish relationships with high quality external genomics partners, transfer genomic assays to external partners for validation, oversee assay implementation in clinical trials and QC data to support primary, secondary and exploratory endpoints supporting Phase 1-3 clinical trials.AccountabilitiesThe Head of Oncology and Cell Therapy Genomics willBuild from the ground up and lead a high-performing, innovative, genomics team responsible for overseeing assay development, implementation and data interpretation from innovative and standard genomics assays.Oversee assays run under regulated approaches (GLP, GCP, GCLP, CAP/CLIA) and QC data to support primary, secondary and exploratory clinical trial endpoints.Understand the entire genomic workflow from sample collection, processing and analysis through data generation.Evaluate, select, and oversee external labs to ensure successful design and execution of clinical assays, including validation, longitudinal performance and data quality. Review and approve genomics related components and interpretation of data in regulatory submissions (INDs, NDAs, BLAs, PMAs etc.).Attend and participate in key program team meetings (e.g. clinical and translational subteams) to provide insight and support for NGS, PCR, ddPCR, RNASeq, Nanostring, single cell analysis, spatial transcriptomics and other genomic-based assays. Collaborate with translational scientists to design experiments that leverage genomic data to support clinical drug development.Collaborate with individuals from other functions including Computational Oncology to further analyze and interpret data in context with other clinical data. Recruit, mentor, develop and retain talent.Education And ExperienceA PhD, MD, or MD/PhD in genetics, molecular biology, or related discipline with at least 8 years of relevant experience beyond post-doctoral training, including at least 2 years of industry experience supporting oncology clinical development.Experience in establishing a genomics laboratory.Prior management experience preferred including recruiting, coaching and developing key talent required.Strong scientific background and experience with assay development and validation across technology platforms in genomics, especially those that are employed in clinical trials (e.g. NGS, WES, WGS, RNASeq, PCR, ddPCR and Nanostring).Experience with outsourcing and working with external academic and CRO partners to develop/transfer assays, oversee data generation/analysis and delivery of high-quality data from global clinical trials under regulated settings (GLP, GCP, GCLP and CAP/CLIA etc.).Familiarity with clinical documents and processes, such as clinical protocols, informed consent forms, laboratory manuals, sample management forms Data transfer agreements, etc.Experience with advanced analysis tools such as deep learning algorithms or AI and/or other technologies such as molecular pathology, flow cytometry a plus.Experience identifying, evaluating and establishing genomics partners to support global clinical trials in countries including Japan, China, Brazil, and European countries.Experience supporting external partner identification and analytical validation for developing and filing of genomics-based companion diagnostics (nice to have)Strong written and oral communication skillsTravel RequirementsAbility to drive to or travel to conferences, partner meetings, laboratory audits as needed, including overnight trips. Some international travel may be requiredRequires approximately 5 - 15% travelWHAT TAKEDA CAN OFFER YOU: 401(k) with company match and Annual Retirement Contribution PlanTuition reimbursement Company match of charitable contributionsHealth & Wellness programs including onsite flu shots and health screeningsGenerous time off for vacation and the option to purchase additional vacation daysCommunity Outreach ProgramsAbsent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. US field-based employees must be fully vaccinated as a condition of employment, absent an approved religious or medical reason. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. If you are contacted by a Takeda recruiter about your job application, we encourage you to seek more information on the applicable guidelines for the Business Unit/Function to which you have accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.Base Salary Range: $ Range Min to $ Range Mid, based on candidate professional experience level. Employees may also be eligible for Short Term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. This posting is made in compliance with Colorado''s Equal Pay for Equal Work Act, C.R.S. § 8-5-101 et seq.Empowering Our People to ShineDiscover more at No Phone Calls or Recruiters Please.LI-JT1EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Created: 2025-10-04