Principal Scientist-DMPK

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda''s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:The DMPK Principal Scientist will provide nonclinical ADME support for Gastrointestinal, Liver and Neuroscience areas spanning discovery, development, and post marketing phases. You will be a DMPK representative on several project teams and will also write relevant sections of non-clinical/clinical protocols and regulatory filings. You will work with drug safety, modeling, clinical pharm, CMC, and other functions to design studies, project clinical dose regimens for new modality therapies. You will liaise between DMPK and multi-disciplinary R&D departments to achieve discovery and development team goals.How you will contribute:Be a DMPK representative on discovery, early and late development, Business Development project teams. Liaise between relevant areas to advance project team goals promptly.Contribute to design of animal and clinical study protocols. ADME analysis.Write DMPK sections and reviewing sections from other functions for regulatory submissions.Develop interdisciplinary collaborations and ensure that important nonclinical data and priorities are integrated into overall project team strategies.Minimum Requirements/Qualifications:Ph.D. in pharmaceutical sciences or related disciplines with a minimum of 6 years of Pharma experience as a DMPK scientist, with deep understanding of some of the biologics and small molecule therapeutics research and development.4 years of project team DMPK support experience with biologics drug development is required.Knowledge of technologies used in new modality therapeutics.Research track record.Experience in late-stage development and registration.Knowledge of PK, metabolism, DDIs, and regulatory guidance is required.What Takeda can offer you:Comprehensive Healthcare: Medical, Dental, and VisionFinancial Planning & Stability: 401(k) with company match and Annual Retirement Contribution PlanHealth & Wellness programs including onsite flu shots and health screeningsGenerous time off for vacation and the option to purchase additional vacation daysCommunity Outreach Programs and company match of charitable contributionsFamily Planning SupportFlexible Work PathsTuition reimbursementMore about us:At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Created: 2025-11-15