Principal/Senior Downstream Bioprocessing Engineer

We are experiencing a technical issue with the Careers Website. At the moment, applications are not possible. We are working on resolving the issue as soon as possible. Thank you for your patience.Principal/Senior Downstream Bioprocessing EngineerA career with MilliporeSigma is an ongoing journey of discovery: our 60,300 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.MilliporeSigma has an exciting opportunity to join the Applications team in BioProcessing''s Single-Use & Integrated Systems R&D organization! The mission of the Applications team is to understand customer needs and influence design of systems for integrated and continuous manufacturing of mAbs and manufacturing of novel modalities such as viral vectors. As a key part of the Application Team, the Principal/Senior Bioprocessing Engineer will help drive a successful product development and launch through focused customer interactions, literature review and lab experimentation. By leveraging and building your expertise in chromatography and filtration technologies, you will play a key part in the development of systems that will shape future of biologics manufacturing by being a creative, analytical, and a proactive thought leader in the rapidly growing and dynamic application space.Location: Based at our Bedford, MA campus.Your Role:* Own the efforts to explore, characterize, and assess the performance of existing and new technologies for intensified downstream bioprocessing applications* Influence product development to meet strategic and technical objectives* Research literature, attend conferences, and interact directly with customers through specific collaborations to keep current with the bioprocessing end user''s process design targets, performance expectations, technical advancements, and general bioprocessing needs* Deliver presentations summarizing technical results and thought leadership both internally and externallyWho you Are:Minimum Requirements* Bachelor''s Degree in Chemical/ Biochemical Engineering/ Chemistry/ Biomedical Engineering (or related discipline) 7-10 years of experience, Masters 6-8 years of experience, PH.D. 3-5 years of experience* Working in the laboratory setting, planning, conducting, documenting, and analyzing data from hands-on experimental work either in industry, or, through your academic pursuits* You are experienced and well-versed in downstream purification of biologicals by clarification, chromatography, and other filtration techniques, and can understand the importance of each from holistic process standpoint* Domestic and international travel may be requiredPreferred Qualifications* Expert in Downstream Bioprocessing purification* Motivated, team-oriented engineer, and enjoy mentoring junior scientists and engineers while creating well-designed laboratory experiments and drawing significant conclusions from the results* Excellent problem solving & analytical skills* Demonstrate an ability to communicate effectively with peers, customers, vendors, and managers* Excellent written communication skills with ability to generate and contribute to publications and publication-quality documents* Experience in continuous processing and process analytical technologies is a plusWhat we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences.We celebrate all dimensions of diversity. We believe that it drives excellence, innovation, and human progress. We care about our customers, patients, and our rich mix of people. This diversity strengthens our ability to lead in science and technology.We are committed to creating access and opportunities for all and empower you to fulfil your ambitions. Our diverse businesses offer various career moves to seek new horizons.Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to bring their curiosity to life!Curious? Chat with one of our curious minds on our interactive Q&A platform and catch a glimpse of our people, values, and culture. You can also apply and find more information at you would like to know more about what diversity, equity, and inclusion means to us, please visit you are a resident of NYC, Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.As an employee of the Company, you will be required to comply with all of the Company''s COVID-19 safety protocols and policies. The organization has currently suspended enforcement of its COVID-19 Vaccination Policy, but that policy may be reinstated by the Company in its discretion.Job Requisition ID: 255069Location: BedfordCareer Level: D - Professional (4-9 years)Working time model: full-timeNorth America DisclosureThe Company is committed to accessibility in its workplaces, including during the job application process. Applicants who may require accommodation during the application process should speak with our Candidate Services team at 844-655-6466 from 8:00am to 5:30pm ET Monday through Friday. If you are a resident of a Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.Notice on Fraudulent Job OffersUnfortunately, we are aware of third parties that pretend to represent our company offering unauthorized employment opportunities. If you think a fraudulent source is offering you a job, please have a look at the following information.Nearest Major Market: BostonJob Segment: R&D, Product Development, Biochemistry, Developer, Research, Science, Technology

Created: 2025-11-15