Laboratory Technician

Job DescriptionThe contractor will collaborate with a multidisciplinary team in an interactive laboratory environment, contributing to collaborative projects with the goal of developing probes and drug lead candidates against Client targets aligned with the Antiviral Program for Pandemics (APP). They will apply cutting-edge cell biology and bioassay technologies for the development of screening assays and will be involved in all aspects of the implementation of small molecule screening programs including assay design, assay development and optimization, pilot and high-throughput screening, data analysis, and follow-up studies in support of structure-activity relationship and mechanism of action studies for the development of Client pharmacological probes. Minimum Education Bachelor''s Resume Max Pages 3 Certifications & Licenses * B.S. or M.S. in Biology or sufficient work experience in a biology lab. * Preferred minimum of one (1) year of related experience in Biosafety Level 2 or higher research environment. Skills (Ranked By Priority) 1. Skill at maintaining accurate and detailed records of laboratory experiments. 2. strong communication skills, both oral and written. 3. bility to work well with others. 4. Excellent organizational and time management skills. 5. bility to multi-task, set priorities and pay close attention to detail. 1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_ Software * Powerpoint * Outlook Field of Study * Biology DELIVERABLES * Work products and documents related to developing research plans and Research Col-laborative Agreements; work with staff on grant/funding applications co-authored with NCATS colleagues and external collaborators. - Ad-Hoc * Work products and documents related to developing and optimizing cell-based and tis-sue-based infection models, including BSL2 and BSL3 viruses,; analyze experimental results; organize findings into tables and figures. - Daily * Work products and documents related to evaluating new techniques and instruments; search literature; propose, design, and test alternative assays; confirm assay results; de-termine EC50/specificity; develop secondary assays. - Daily * Work products and documents related to maintain and update notebooks and equipment; prepare technical reports, summaries, and manuscripts; prepare oral presentations and posters. - Daily STATEMENT OF WORK DETAILS functional responsibility Plans, executes, and arranges laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research. description * Perform routine experiments and tests, including tissue culture, cell separation, protein, and quantitative and qualitative analysis. functional responsibility Operates laboratory machines and instruments; and prepares specimens and equipment for use. description * Work with staff on the maintenance of laboratory cell lines. description * Prepare materials and equipment for experiments. description * Maintain stocked supplies and records of working reagents, including fixatives, buffers, solvents and staining. description * Work with a variety of routine and specialized laboratory instruments and equipment in the laboratory. functional responsibility Performs sample management and storage. description * Store new samples, update database, retrieve samples with proper authorization. description * Perform quality control procedures necessary to ensure the accuracy of each test system, sample processing, storage and inventory of samples. description * Perform processing, description and analysis of samples. description * Work with staff to implement storage and distribution of biological samples for future scientific research. functional responsibility Analyzes, documents and reports on all procedures performed. description * Convey and discuss research results with team lab members. description * Update and maintain written laboratory record of the work. description * Collect and enter research data into laboratory notebooks and databases. description * Maintain and update laboratory notebooks and databases; and enter experimental data into spreadsheet and conduct statistical analysis. functional responsibility Maintains inventory of laboratory supplies. description * Ensure that supplies and consumables are ready and on hand as necessary for maximum efficiency in the laboratory. functional responsibility Cleans and sterilizes instruments, glassware and equipment. description * Work with staff to cover glassware washing, media preparation, and autoclaving. functional responsibility Plan execute and arrange laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research. description * Perform routine experiments and tests, including tissue culture, cell separation, protein, and quantitative and qualitative analysis. description * Perform primary cell culture techniques and immunohistochemistry. description * Follow established procedures and protocols; utilize aseptic technique to perform experiments. description * Perform a variety of laboratory techniques and procedures. description * Perform experiments on samples according to protocols. description * Perform routine experiments and tests; follow established procedures and protocols. functional responsibility Maintains inventory of laboratory supplies and initiates purchase orders. description * Work with staff to maintain stocked supplies and records of working reagents, including fixatives, buffers, solvents and staining. functional responsibility Performs routine equipment maintenance. description * ssist in troubleshooting and calibrating various laboratory equipment and instruments. functional responsibility Plan execute and arrange laboratory experiments, new techniques and procedures; and performs laboratory techniques relating to scientific research. description * Perform fundamental procedures required for research projects. functional responsibility Analyzes, documents and reports on all procedures performed and produces detailed reports for use by senior staff. description * Prepare reports and summaries based on results and findings. functional responsibility Performs advanced equipment maintenance. description * Work with the Antiviral Program for Pandemics Advanced Models and Cell Based Client-covery team to establish and validate a portfolio of traditional cell-based assays for high throughput drug screening and complex physiologically relevant 3D tissue models as predictive screening platforms to study viral infections and drug testing. 1 description * Conduct nucleic acid purifications and assays including but not limited to quantitative real-time PCR, digital droplet PCR, RNA sequencing library preps. 2 description * Virus culture, virus expansion, virus tittering, virus stock maintenance, virus stock se-quencing. 3 description * Cell line culturing, passaging, plating, stock maintenance. 4 description * Work closely with the members of the Advanced Models and Cell Based Discovery team in assay support, e.g. HTS assays, high content imaging assays. 5 functional responsibility Trains staff in performing routine laboratory tests and procedures. description * Effectively communicate and present data. description * Keep accurate and complete records of all scientific experiments according to estab-lished procedures. description * Draft technical reports and support manuscripts and patent applications. functional responsibility Provides insights and expertise and recommends new strategies and approaches. description * Perform viral detection assays in a variety of cell and tissue-based platforms. description * work with team on the interpretation of assay outcomes. description * nalyze the experimental results and organize findings into tables and figures. description * nalyze and organize experimental results using data analysis/visualization software. 1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_

Created: 2025-10-04