Senior Scientist

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients'' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.Senior Scientist - DownstreamThe Senior Scientist - Downstream in Manufacturing Sciences & Technology supports the commercial and late stage clinical manufacturing of biopharmaceuticals in the area of purification and primary recovery. The successful candidate will be a subject matter expert and key contributor to a highly technical, diverse, and collaborative team of scientists and engineers. MS&T scientists and engineers contribute to cross-functional teams to meet highly visible business objectives. The position offers the opportunity to interface with Manufacturing, Manufacturing Support, Process Development, Quality Assurance, Analytical, and Global Regulatory Sciences groups.Responsibilities include but are not limited to:Leading downstream support for commercial and late stage clinical manufacturing process by providing technical expertise for investigation of downstream process deviations, root cause analysis, CAPAs, and process improvements.Leading downstream support for process technology transfer, process validation, and CMC documentation preparation.Leading downstream support for regulatory filing preparation, agency inspection, and agency inquiry responses.Leading technical studies. Following GLP/GMP procedures to design and execute experiments to solve process-related manufacturing investigations or to enable the technology transfer of new processes to larger scale manufacturing through the use of laboratory and pilot scale-down models in protein chromatography, viral inactivation, viral filtration, ultrafiltration/diafiltration, membrane filtration, depth filtration, and centrifugation.Documentation of experimental data and results, data verification, interpretation of data with respect to the laboratory protocol and the manufacturing process, and preparation of final reports to summarize the findings.Effective collaborations with Manufacturing, Manufacturing Support, Process Development, Quality Assurance, Analytical and Global Regulatory Sciences groups. Strong communication and technical writing skills are required.Evaluation of new process technologies.Qualifications:BS or MS or PhD in Chemical/Biochemical Engineering or Biochemistry related field. BS or equivalent with a minimum 5 years relevant industrial experience, MS or equivalent with minimum of 4 years relevant industrial experience, Ph.D. with 2-4 years of relevant experience.Solid scientific understanding of protein purification and protein stability is required. Lab experience with AKTA purification and ultrafiltration/diafiltration operations is preferred.Critical qualities include a high level of scientific curiosity and critical thinking ability, good verbal/written communication skills to interface with multi-disciplinary teams.Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to [Click Here to Email Your Resumé]. Visit /eeo-accessibility to access our complete Equal Employment Opportunity statement.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Created: 2026-03-07