Sr. Vice President, Global Medical Affairs

Job Description Summary: The Sr. Vice President, Global Medial Affairs is the head of the Global Medical Affairs (GMA) function and is responsible for providing strategic and operational leadership to GMA organization by designing, integrating and addressing the strategic interests / needs of business and scientific stakeholders across all PTC therapeutic areas / indications. This individual is also responsible for aligning the objectives of the GMA organization with the broader strategic objectives of the global organization which includes partnering with commercial, development, regulatory and other key functions.The incumbent manages a global team capable of developing programs that deliver commercial and scientific results and optimize patients'' long-term health outcomes. He/she is also accountable for ensuring that the programs / activities associated with the medical affairs function are conducted in accordance with applicable regulatory requirements.He/she manages direct reports.The incumbent works cross-functionally with internal departments and external resources on Medical Affairs related issues.The Sr. Vice President, Global Medical Affairs is accountable for adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.Job Description:ESSENTIAL FUNCTIONSPrimary duties/responsibilities:Leads and drives an efficient and effective global Medical Affairs function.Collaborates with the commercial organization, global medical affairs staff and representatives of the clinical, regulatory and commercial functions to develop integrated medical Affairs strategies that aligns with, and supports, the global commercial strategy and associated departmental initiatives.Develops and manages a global key opinion leader (KOL) strategy that supports PTC''s commercial relationships with KOLs and other external key stakeholders (e.g. academic institutions with a relevant medical / scientific community); Ensures the strategies and relationships are established and maintained; responsible for hands-on development and management of peer-level KOL / key stakeholder collaboration with Patient Advocacy department, may represent PTC at patient advocacy group meetings or other professional medical and advisory collaboration with Clinical Development department, designs, implements and manages global registries or outcomes surveys that combines the ability to meet post-marketing regulatory commitments and other valuable longitudinal outcomes data to support and enhance product value.Provides medical oversight for the scientific aspects of PTC satellite symposia, medical congresses, workshops and other meetings, including speaker contacts and post-conference partnership with the Commercial and Clinical development teams, leads the design and development of registries, medical information, medical publication / communication plans that supports inline and pipeline product strategies.Accountable for ensuring that promotional and other commercially-oriented materials receive medical review / approval.Ensures that a comprehensive medical training program is provided to maintain the highest standards of internal knowledge of products, markets and disease area.Ensures timely and accurate medical information is disseminated to health care professionals through the management of a global medical information collaboration with Market Access, develops strategies to present relevant medical data to commercial and government payers.Contributes to the development of key medical messaging and its translation into commercial messaging; contributes to the development of PTC''s overall communication strategy and ensures that communications incorporate key medical messaging.Establishes, leads and directs the cross-functional global grants review committee that reviews / approves investigator initiated studies and provides strategic framework to ensure that approved grant support PTC''s lifecycle plans, publications plans and marketing strategies.Provides medical support to regulatory and market access activities and to pre - launch, launch and ongoing sales and marketing strategies.Ensures that medical affairs activities are conducted in compliance with appropriate safety, environmental, financial, legal, and regulatory requirement.Develops and manages global medical affairs budget.Manages, coaches, develops and mentors direct reports.KNOWLEDGE/SKILLS/ABILITIES REQUIRED* Minimum level of education and years of relevant work experience.Medical degree (M.D.), PhD or PharmD and a minimum of 15 years of progressively strategic experience in medical affairs roles in a pharmaceutical, biotechnology or related environment including significant global leadership experience or equivalent combination of medical and industry experience.* Special knowledge or skills needed and/or licenses or certificates required.Demonstrated ability to build and manage a strategic medical affairs organization while also retaining responsibility for the hands-on execution of the associated programs.Demonstrated track record of success supporting the commercialization of an orphan, rare disease and/or specialized drug(s).Experience developing and managing a global budget.Direct management of, and hands-on involvement in, full life cycle medical/clinical research and medical education activities for marketed biotechnology or pharmaceutical products.Demonstrated ability to apply medical/clinical expertise to the development of a global medical affairs function that advances the company''s commercial and clinical development -depth understanding of the clinical trials process with demonstrated ability to design and implement programs and initiatives designed to address specific strategic objectives.Experience evaluating and approving proposals for investigator-initiated studies, ensuring that they are aligned with the company''s clinical and commercial strategies.Experience overseeing the management of study grants and study progress and monitoring.Hands-on experience interpreting the impact of new research findings on current medical thinking with ability to leverage this data to build and foster disease management frameworks.Demonstrated leadership ability and experience managing, coaching and mentoring direct reportsAbility to influence without direct authority.Proficiency with Microsoft Office.Excellent verbal and written communication and skills.Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.*Special knowledge or skills and/or licenses or certificates preferred.Experience in one or more of the following therapeutic areas: genetic disorders, neurology, metabolic conditions.Experience in orphan/rare diseases.Experience managing patient registries.Fluency in a second language.* Travel requirements25-50%*Physical requirements (only note if the job requires physical capacity beyond general office work)Office-based position or remote with requirements to travel to office as needed.**At PTC Therapeutics we are seeking candidates in the United States who are fully vaccinated against COVID-19 or who will be fully vaccinated by the time they begin the position.EEO Statement: PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.Click here to return to the careers page

Created: 2026-04-04