Computational Protein Design Scientist | Protein ...

Computational Protein Design Scientist | Protein Design | Synthetic Biology | Python | Hybrid, San FranciscoComputational Protein Design Scientist | Protein Design | Synthetic Biology | Python | Hybrid, San FranciscoGet AI-powered advice on this job and more exclusive features.Direct message the job poster from EnigmaFounder @ Enigma | Creator of Vision to Venture Podcast & The Neural Network CommunityComputational Protein Design Scientist | Protein Design | Synthetic Biology | Python | Hybrid, San FranciscoWe are seeking a Computational Protein Design Scientist to join a team operating at the intersection of generative AI and synthetic biology. You will play a key role in designing and engineering proteins for specific functions, such as DNA editing. This is an opportunity to help shape and grow an organisation that applies cutting-edge artificial intelligence to longstanding scientific challenges. Leveraging your computational expertise and biochemical understanding of proteins, you will generate insights to improve protein functionality and work across foundational machine learning and experimental platforms to integrate AI generations with lab validation data seamlessly.About UsWe are an early-stage, venture-backed startup pioneering advancements at the intersection of AI and life sciences. By developing generative AI models for computational control over biological processes, we aim to make biology programmable, driving innovation in health and sustainability. With teams based in multiple locations, including London and San Francisco, we are passionate about solving complex challenges and maximising global impact. Our team is led by a founder with expertise in breakthrough protein design technologies and AI applications.We are committed to fostering a collaborative environment where curiosity thrives. Join us to shape transformative technologies and a dynamic, innovative company culture.About YouExpert in Computational Protein Design: You have a proven ability to use computational tools and biochemical or structural biology knowledge to design proteins for functional requirements and synthetic biology applications.Strong Data Scientist: You have experience leading data-driven projects to uncover biological insights.Accomplished Scientist: You hold a PhD (or equivalent experience) in computational biology, bioinformatics, computer science, biochemistry, structural biology, physics, biophysics, or a related field, with research experience in protein biochemistry and computational methods.Collaborative Partner: You have worked closely with experimental teams to achieve protein design objectives.Project Owner: You have a track record of delivering impactful research or commercial projects, evidenced by publications, patents, or other significant contributions.Connector: You thrive on bringing people together and are skilled at communicating complex scientific concepts to diverse audiences.Mission-Driven Innovator: You are motivated by solving real-world problems and achieving meaningful impact.Adaptable Problem Solver: You excel in fast-paced, dynamic environments and are skilled at optimising processes to improve efficiency and scalability.What Sets You Apart (Preferred but not required):Experience applying generative AI or machine learning in synthetic biology.Familiarity with engineering gene-editing tools (e.g., nucleases, integrases).Expertise in homology-based bioinformatics and large database analysis.Previous experience scaling a biotech startup.Key ResponsibilitiesProtein Design with Generative AIGenerate and optimise designs with proprietary AI models for experimental validation.Collaborate with lab teams to refine processes and strategies.Use experimental results to enhance model performance and improve success rates.Partner with machine learning teams to fine-tune and optimise AI models.Collaboration and CommunicationBridge the gap between AI development and experimental validation teams.Foster innovation and alignment across teams.Tool and Workflow EnhancementProvide feedback on AI models and software tools.Improve data management systems and workflows.Scientific Excellence and GrowthConduct publication-grade research and stay updated on synthetic biology developments.Share knowledge through internal and external presentations.Attend and contribute to relevant conferences.What We OfferWe provide a competitive compensation and benefits package, including health insurance, pension/401(k) contributions, generous leave policies, travel opportunities, and more. This role offers a stimulating work environment and the chance to shape the future of synthetic biology using cutting-edge generative AI.We welcome applicants from all backgrounds and are committed to building a team that reflects a diverse range of perspectives and skills. The role is based in San Francisco.Contact InformationPlease send your resume as soon as possible to Protein Design Scientist | Protein Design | Synthetic Biology | Python | Hybrid, San FranciscoSeniority levelSeniority levelMid-Senior levelEmployment typeEmployment typeFull-timeJob functionJob functionInformation Technology, Research, and EngineeringReferrals increase your chances of interviewing at Enigma by 2xGet notified about new Computational Scientist jobs in San Francisco Bay Area.San Francisco, CA $150,000.00-$250,000.00 7 months agoSenior Staff Scientist, Computational ChemistryMilpitas, CA $115,900.00-$197,000.00 2 weeks agoResearch Scientist - Noise Reduction AlgorithmsApplied Scientist, Structural Design IntegritySunnyvale, CA $136,000.00-$223,400.00 2 days agoAI Trainer for Thermodynamics (Freelance, Remote)Research Scientist - Electron Beam Source DevelopmentMilpitas, CA $130,400.00-$221,700.00 4 days agoResearch Scientist, Design and SimulationQuantum Algorithms Researcher (Chemistry/Materials Science)San Francisco, CA $149,700.00-$393,200.00 3 months agoSenior Scientist, Quantum Sensing (Control)Fundamental AI Research Scientist - FAIR (PhD)Menlo Park, CA $117,000.00-$173,000.00 2 weeks agoSenior Bioinformatics Scientist, Research and Early DevelopmentPostdoc - Conductive Oxide Device PhysicsLivermore, CA $120,000.00-$155,000.00 1 month agoQuantum Algorithms Numerics Specialist, Quantum AIR&D Engineer, Detector Design, Model, and AnalysisFundamental AI Research Scientist, Language - FAIR (PhD)Science: Physics (2025-26 School Year Eligibility Pool)Research Scientist (Electron Optics Systems)Sheng Lab - Junior or Assistant SpecialistWe’re unlocking community knowledge in a new way. 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Created: 2025-09-17