Research Scientist II -HCMG - RADC - Full-time-20871

OverviewResearch Scientist II -HCMG - RADC - Full-time-20871 at Rush University Medical CenterLocation: Chicago, IllinoisBusiness Unit: Rush Medical CenterHospital: Rush University Medical CenterDepartment: Rush Alzheimers Dis Ctr-ResFacWork Type: Full Time (Total FTE between 0.9 and 1.0)Shift: Shift 1Work Schedule: 8 Hr (8:00:00 AM - 4:30:00 PM)Rush offers exceptional rewards and benefits. Pay Range: $32.00 - $52.08 per hour. Salaries are determined by factors including education, experience, skills, internal equity, and market data. Offers may vary by case.Summary: The Staff Research Scientist will design and perform complex scientific research experiments. This person will lead research efforts on human iPSC-based disease modeling or/and CRISPR gene perturbations. The job will perform experiments, analyze data, compile results, and monitor quality control processes to ensure integrity of research. The position will utilize knowledge of molecular biology, neurobiology, cell biology, human genomics, and stem cell biology. This person will troubleshoot and evaluate data, and prepare manuscripts based on experimental results. The work requires the application of highly specialized knowledge of brain development and human genetic/epigenetic regulations. Related techniques include human iPSC cultures, neural differentiation, brain organoid cultures, high-content imaging, molecular biology, viral packaging, CRISPR gene perturbations and data analysis. Exemplifies the Rush mission, vision and values and acts in accordance with Rush policies and procedures.ResponsibilitiesMentor technicians and graduate studentsGenerate multi-cellular 2D and 3D culture models to incorporate different cell typesDevelop cellular, molecular, and functional assays to examine AD phenotype in the dishConduct gene perturbation experiments to test AD candidate genesCollect and analyze multi-module data, including imaging, FACS, qRT-PCR, targeting sequencing etc.Coordinate other team members to successfully execute the research planPrepare and/or publish scientific papers and manuscriptsContribute to grant writingCommunicate with other RADC teams on related projectsPlan and conduct statistical analysis of dataPrepare abstracts and meeting materials to present (slides, posters) within scientific groupPlan meetings (investigator meetings and other scientific/operational meetings)Design and execute complex research proceduresDevelop and perform routine and complex protocols for research programsAssist in developing, implementing, and monitoring quality activitiesCollaborate with principal investigators in determining study design and performing statistical analysesPerform and develop routine and complex computational and database methods for implementationParticipate in meetings with principal investigator and research staff and evaluate/interpret data, develop methodologies, evaluate lab proceduresMay oversee the work of laboratory personnel including training and development as well as daily work direction/delegation/prioritizingQualificationsPh.D. with 3 years expertise in Neuroscience, Cell biology, Developmental biology, Stem cell biology, molecular biology, or related field or a Master’s degree with 6 years of experienceExcellent skills and experience in human iPSC cultures, neural differentiation, and brain organoid culturesExcellent skills and experience in assay development and high-content imagingExcellent skills and experience in molecular biology and CRISPR gene perturbationsExcellent project planning, organization, and problem-solving skillsExcellent communication and interpersonal skillsProven ability to work independently and in collaborative team environmentsAbility to work for 8 hours daily in the labDisclaimer: The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of duties, responsibilities, or requirements.Other InformationRush is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics. #J-18808-Ljbffr

Created: 2025-09-17