Vertex Pharmaceuticals: MSAT Senior Principal ...

OverviewVertex MSAT team is seeking a Senior Principal Data Scientist to join a growing team in support of commercial Cell and Gene Therapy programs. This position will be responsible for leading and providing technical support in alignment with defined program priorities pertaining to data acquisition, analysis, trending, visualization, and reporting.Key ResponsibilitiesIdentify and develop technical solutions to enable program and company goals.Lead development of data trending visualizations using Statistica and for process parametersLead the Development of Routine Data Visualization charts and toolsDevelop scripts for automated reporting of trends and correlationsDevelop visualization for acknowledged alarm reporting and trendingAuthor SOPs and work instructions to standardize the process of pulling trend reports from TIBCO.Author technical protocols, reports, and other GMP supporting documents.Contribute to developing technical solutions to enable program and company goals.Ability to work within a team and independentlyProvide regular (weekly) updates towards project goals.Minimal RequirementsPhD, MS, or BS in relevant science or engineering discipline.PhD with 5+ years, MS with 7+ years, or BS with 9+ years of experience.Significant experience with data software packages including Statistica and Spotfire at a minimum.Experience with cell therapy or large-scale GMP manufacturing for biopharmaceutical manufacturingExperience with designing process monitoring tools to detect OOT/OOEExperience with designing process visualization tools to show process trendsExperience with designing automated trend outputsExperience with process characterization and process control strategy preferred.Experience with cGMP regulations/guidance and with regulatory agency inspections preferred.Experience with inline process analytical technologies for assessment of manufacturing performanceExperience working and leading projects in a matrixed organizationExperience working with external partners (CMOs, vendors, etc.).Excellent communication skills, both written and verbalAbility to travel, nationally and internationally, up to 10 - 15%.Flexibility to work on site a minimum of 3 days per week.Pay Range$164,900 - $247,400Disclosure StatementThe range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex DesignationHybrid-Eligible Or On-Site EligibleFlex Eligibility StatusIn this Hybrid-Eligible role, you can choose to be designated as:1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any pany InformationVertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at #J-18808-Ljbffr

Created: 2025-09-17