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Research Associate

Escalante - San Francisco, CA

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Job Description

OverviewJoin to apply for the Research Associate role at Escalante. Escalante enables the next generation of biological insights through scalable, functional, single-molecule proteomics by combining molecular biology, protein biochemistry, and artificial intelligence. We aim to build AI models that predict how cells respond to therapeutic perturbations, transforming biology and drug discovery with new measurement technologies and datasets. We rely on our people, our ambition, and our willingness to challenge the way science is done.The OpportunityAs a Research Associate at Escalante, you will work with an interdisciplinary group of scientists and engineers to develop the next generation of scalable single-molecule proteomics. This is a wet-lab based role where you will assist the biology team to run high-throughput proteomics assays for machine learning model training, develop robust assays for QC and validation of our platform, and collaborate with automation engineers to scale our process. Your work will directly contribute to our core platform and help guide Escalante’s trajectory. This is a full-time on-site role in San Francisco, California.ResponsibilitiesExecute protein purification and sequencing experiments using established protocols, with opportunities to refine and improve methods.Assist scientists in optimizing workflows and troubleshooting routine issues.Operate and maintain lab automation systems to ensure accurate, efficient experimental execution.Maintain and culture mammalian cell lines, including routine passaging, monitoring cell health, and ensuring aseptic technique and accurate record-keeping.About YouBachelor’s degree in biology or related field, with 2–5 years of industry experience.Hands-on experience in protein purification and/or sequencing workflows.Familiarity with mammalian cell culture techniques.Outstanding ability to record and communicate scientific work.PlusesExperience with pooled library approaches.Background in chemical conjugation methods.Basic familiarity with Python pensationCompetitive salary + equity + benefitsBenefitsGenerous paid time off, 100% health coverage, employee stock option plan, paid parental leave, office snacks and beveragesEqual Employment OpportunityEscalante is committed to equal employment opportunity regardless of race, color, ancestry, national origin, religion, sex, age, sexual orientation, gender identity and expression, marital status, disability, or veteran status. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. #J-18808-Ljbffr

Created: 2025-09-18

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