Medical Director, Oncology Clinical Development (...

Reporting to the Vice President, Clinical Development, the Medical Director will be responsible for clinical research activities advancing the development of Hengruis clinical portfolio outside of China and will also have responsibility for engaging in medical dialogues with relevant scientific and medical leaders to lead clinical data generation activities.This role requires a physician capable of developing and executing oncology clinical trials in support of the successful clinical development, regulatory filing and initial market launch of innovative Oncology agents.Collaborate with physicians, scientists, regulatory professionals, biostatisticians, executive staff and others in a complex matrix environment to develop and execute phase 1-3 interventional clinical trialsEnsure high quality protocol development aligned with the Clinical Development Plan to effectively determine a medicines potential efficacy, safety profile, key areas of product differentiation and value to patient in the shortest possible timeframe.Use medical expertise to contribute to the end to end (protocol concept to final study report) to ensure scientific integrity and timely delivery of clinical trials which ensure consistency with the clinical development strategy for regulatory approvals, reimbursable medicines, and successful lifecycle management; demonstrate ability to incorporate global considerations into decision makingInterpret and summarize study results consistent with objectives to define safety, efficacy, pharmacokinetic/pharmacodynamic, and patient reported outcomes, and applicability of data to the targeted patient population.Assume medical responsibility for clinical trials with active participation in real-time medical monitoring of studies, including patient eligibility assessment, study design questions, and addressing urgent safety questions (with inclusion of Safety/ PV as relevant).Assume responsibility for medical review of clinical trial data, both directly as needed and/or via oversight of delegated medical review. Oversee blinded review of data packages intended for IDMCs.Review/monitor safety data in collaboration with pharmacovigilance group for active clinical studies.Participate in the authoring of clinical study reports and regulatory documents and collaborate with colleagues in Regulatory Affairs, CMC, Toxicology, Research, Pharmacology to respond to health authority and ethics committee queries.Collaborate with Principal Investigators in the evaluation and assessment of publications (abstracts, posters, manuscripts) associated with clinical work extensively to develop long-term strategic partnerships with thought leaders both internally and externally, in support of Hengruis vision.Understand biological mechanisms, clinical strategy, scientific interpretation of disease and target-based literature.Participate in Oncology Clinical Development-wide initiatives and workstreams as appropriate.Job requirementsWe are looking for professionals with the following required skills to achieve our goals:Medical degree with completion of post medical education clinical residency trainingBoard/registration qualifications in medical oncology or hematology3+ years of oncology experience in pharmaceutical/biotechnology industry and clinical practice experience in the fields noted aboveDocumented academic and/or clinical research publication history or history of medical practice in the fields noted above.Strong working knowledge of the clinical drug development process with experience in the conduct/participation of clinical trials (investigator initiated, company sponsored or cooperative group trials) and their subsequent publications.Experience in regulatory requirements to support registration, including knowledge and adherence to GCP principlesIf you have the following characteristics, it would be a plus:Active certification in medical oncology by the American Board of Internal Medicine or equivalentExperience in leading oncology clinical trials, including experience with study design, data review/interpretation and the overall clinical development processRobust knowledge of disease-specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment guidelines evolutionBenefits:We offer a comprehensive benefits package including medical, dental, and vision insurance; paid time off; a 401k retirement plan with company match; and company-paid life and short-term disability insurance. Additional voluntary benefits (e.g., FSA, DCSA, supplement life insurance, etc.) are available.Schedule: Monday to Friday

Created: 2025-09-24