Associate Scientist, Assay Development (Proteins & ...

Associate Scientist, Assay Development (Proteins & Biophysics)IRIS Kinetics Boston, MA (On-site)About IRIS KineticsAt IRIS Kinetics, we are pioneering next-generation label-free biosensing platforms to transform diagnostics and life sciences. Our technology enables ultra-sensitive, real-time detection of biomolecular interactions, powering both research and clinical applications. We are seeking a highly motivated Associate Scientist to join our growing R&D team and help drive assay development for proteins, antibodies, nucleic acids, and small molecules.ResponsibilitiesAs an Associate Scientist, you will play a key role bridging senior scientists and junior research associates, contributing to assay development while supporting day-to-day lab operations. You will:Design, execute, and analyze experiments for protein, antibody, nucleic acid, and small-molecule interactions.Design, implement, and evaluate surface functionalization and immobilization chemistries for biosensor applications.Optimize and characterize materials and surface chemistries to enhance sensor performance and dependently perform common wet lab techniques (pipetting, aliquoting, titration, pH measurements, reagent prep) and troubleshoot issues as they arise.Develop and optimize immunoassays, including ELISA, for sensitivity and reproducibility.Apply biophysical methods such as BLI (Bio-Layer Interferometry) or SPR (Surface Plasmon Resonance) for kinetic characterization of biomolecular interactions.Support development of assays tailored to the IRIS platform and contribute to validation studies.Train and mentor Research Associates on lab techniques, experimental design, and best practices.Maintain accurate and thorough documentation of experimental protocols, results, and analysis.Contribute to lab organization, workflow efficiency, and maintaining a collaborative team environment.Stay informed about emerging scientific trends and technologies to integrate novel approaches into research activities.Adhere to laboratory safety standards and contribute to the development of Standard Operating Procedures (SOPs).QualificationsRequiredB.S. or M.S. in Biochemistry, Molecular Biology, Biophysics, Biomedical Engineering, or related field.35 years of hands-on industry experience in an assay development, protein science, or biophysics-focused lab.Strong proficiency in wet lab techniques (pipetting, buffer prep, titrations, pH measurement, instrument handling).Demonstrated expertise in protein/antibody handling and immunoassay development (ELISA or similar).Solid understanding of biomolecular interaction kinetics (binding affinity, on/off rates, etc.).Ability to work independently with minimal supervision while collaborating in a team.PreferredExperience with BLI (ex. Octet), SPR (ex. Biacore), or other label-free kinetic analysis platforms.Familiarity with antibody engineering, conjugation, or small-molecule binding studies.Prior mentoring or training of junior scientists.Excellent problem-solving, organization, and communication skills.What We OfferOpportunity to join a fast-growing startup developing breakthrough diagnostics technology.Collaborative and dynamic work environment with room for growth into Scientist petitive salary and benefits.

Created: 2025-09-24