Protein Production & Characterization (RA/Scientist, ...
Nabla Bio - Cambridge, MA
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Nabla Bio is building AI capable of generating biomolecules on demand to probe and treat disease. By combining cutting-edge AI with experimental systems that reflect how drugs behave in humans, we’re designing new kinds of medicines — targeting biology conventional tools can’t reach, and in drug formats built for disease precision, safety, and human impact. Backed by premier investors like Radical and Khosla Ventures, we have forged significant partnerships with leading pharma companies such as AstraZeneca, Takeda, and Bristol Myers Squibb. The Role Fueled by partnerships and increasing demand for internal R&D, we will be looking to you to help scale our antibody expression, purification, and developability measurement pipeline and apply it toward solving hard antibody design problems. This will include: Developing high-throughput HEK and CHO-based antibody expression and purification protocols. Prioritizing top development candidates by characterizing antibodies for key biophysical traits, including but not limited to, affinity, cross-reactivity, stability, polyspecificity, aggregation, and hydrophobicity Performing and improving molecular biology workflows including cloning, PCR, Gibson/Golden Gate assembly, DNA sequencing, and bacterial transformation. Working together with our dry-lab and other wet-lab scientists to establish a rapid and seamless production and testing pipeline for characterizing machine learning generated antibody designs This role has a strong focus on process development and workflows. Qualifications You are a strong candidate if you have led successful multi-month/year projects featuring direct experience in the above. Life science-focused MS or BS with 1-2 years research/industry experience are highly desirable. You must like to work quickly with precision. High aptitude, tenacity, and the foundational knowledge to solve problems outside of your comfort zone is critical. We will invest heavily in training you, and are committed to helping you grow within Nabla and beyond. What We Offer A fast-moving environment where you can build and ship tools that impact real drug programs A small, focused team where your scientific and engineering decisions have outsized impact Highly competitive salary, equity, and benefits package Nabla Bio is an equal opportunity employer. We welcome applicants from all backgrounds and experiences, and strongly encourage candidates from underrepresented groups in science and technology to apply. Reach out at
Created: 2025-09-24