Senior Scientist 1 - Biophysics

We are a fast-growing research and services division in WuXi AppTec and are working on developing cutting-edge multidisciplinary drug discovery platforms combining the latest technologies in biology, chemistry, biophysics, engineering, and informatics. We are seeking a highly motivated and collaborative biophysicist to play an integral role in expanding the capabilities at our site in Natick MA. This position is critical to the successful development, implementation and business operations of biophysics platforms and services for the business unit. Designs and executes novel SPR, TSA, and other biophysics studies, including protein-small molecule interactions, protein-protein interactions, and fragment screening. Analyzes and interprets biophysical data. Works closely with clients to establish assays. Prepares scientific reports and presents scientific data. Develops workflow and processes. Mentors junior scientists in the lab. Works broadly and flexibly with the biophysics business group across different geographic regions. Contribute to troubleshooting, planning, and biophysics strategy as a key member of the biophysics group. Develops and performs orthogonal target engagement, or additional binding assays in line with project requirements. Experience / Education Bachelor's with 14 years’ experience; Master's with 10 years’ experience, or PhD with 6 years’ experience. Master or PhD degree is preferred in Biochemistry or Biophysics. Industry experience in Pharma/Biotech and/or drug R&D process is preferred. Proven hands-on experience with developing and troubleshooting biophysical assays (SPR, MST, DSF/TSA, GCI, ITC and/or MS). Deep understanding of binding kinetics and rigorous data analysis Demonstrated understanding of complex scientific procedures and technical proficiency with in vitro assays. Knowledge / Skills / Abilities: Ability to demonstrate scientific creativity, critical thinking and fast learning capabilities. Outstanding written and oral communication skills. Interpersonal skills to seamlessly fit within a teamwork driven environment. Ability to effectively communicate with internal team colleagues and external clients to promote world class service. Must be able to read, write and understand English. Physical Requirements: Must be able to work in an office environment with minimal noise conditions. Must be able to work in a lab setting with exposure to biohazards, chemicals Must be able to wear appropriate PPE Must be able to work in an environment with variable noise levels Ability to stand/sit/walk for long periods Ability to lift 10 lbs. routinely Ability to crouch, bend, twist, and reach Ability to push/pull 10 lbs. routinely Clarity of Vision An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.

Created: 2025-10-01