Principal Scientist Preclinical Imaging

2 weeks ago Be among the first 25 applicants Get AI-powered advice on this job and more exclusive features. Overview Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With focus on four therapeutic areas — Oncology, Inflammation, General Medicine, and Rare Disease — we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Position Principal Scientist Preclinical Imaging What You Will Do Let’s do this. Let’s change the world. Amgen Comparative Medicine is seeking a Preclinical Imaging Scientist in our Thousand Oaks, CA location. As part of the Comparative Medicine department, you will have a chance to advance the development of novel medicines with a state-of-the-art imaging laboratory, generate decision making data packages across the pipeline (oncology, cardiometabolic disease, inflammation, rare disease, and biomarkers), and have high visibility across the discovery research organization. Key Responsibilities Leverage and manage a state-of-the-art preclinical imaging laboratory (PET, CT, MRI, and radiochemistry) and external CRO capabilities to answer critical scientific questions Partner with multiple therapeutic area researchers to advance the pipeline by running model development, biodistribution, biomarkers, and pharmacodynamic imaging studies Design studies, acquire images and analyze images, interpret data, author study reports, and present to study teams Independently determine laboratory operations including laboratory calendar, maintain an IACUC protocol, radiopharmacy contracts, and safety of all staff Set project timeframes and priorities that allocate imaging resources to align with Amgen’s strategy Represent Comparative Medicine through internal and external presentation and the submission of manuscripts for publication Mentor junior professional team members, interns, and post-docs Serve on the Comparative Medicine Thousand Oaks Leadership Team with a special focus on fostering and integrating the imaging capabilities into the larger organization If a veterinarian, serve on call for clinical coverage on a rotating basis What we expect of you We are all different, yet we all use our unique contributions to serve patients. The vital attribute we seek is a candidate with these qualifications. Basic Qualifications DVM or Doctorate degree (PhD) OR PharmD OR MD in imaging, pharmacology, biomedical engineering, or related field and 2 years of relevant experience Or Master’s degree in imaging, pharmacology, biomedical engineering, or related field and 5 years of relevant experience Or Bachelor’s degree in imaging, pharmacology, biomedical engineering, or related field and 7 years of relevant experience Preferred Qualifications DVM with advanced training such as MS, ACLAM eligible or ACVR eligible 3+ years leading or mentoring scientific staff and managing project portfolios in pharmaceutical or CRO settings Hands-on preclinical imaging experience with mastery of PET, CT, and/or MRI Strong in vivo rodent skills (IV dosing, anesthesia, sample collection) Proficient in quantitative image analysis packages (e.g. Amira, VivoQuant, OsiriX, 3D Slicer, AMIDE, PMOD) Expertise in oncology, cardiovascular, or immune/inflammatory rodent disease models Working knowledge of statistical and data presentation packages (e.g., GraphPad Prism) Familiarity with translational imaging and early clinical development data packages for imaging biomarkers Proven track record of peer-reviewed publications and conference presentations, demonstrating collaboration and high-level contribution Working knowledge of data integrity, data management, and AI-automation of image analysis What you can expect of us We support your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, comprising health and welfare plans for staff and eligible dependents, financial plans to save towards retirement or other goals, work/life balance, and career development opportunities which may include: a comprehensive benefits package, retirement and savings plan with generous company contributions, group medical/dental/vision coverage, life and disability insurance, flexible spending accounts; a discretionary annual bonus program; stock-based long-term incentives; award-winning time-off plans; flexible work models where possible. Apply now and make a lasting impact with the Amgen team. In any materials you submit, you may redact or remove age-identifying information. You will not be penalized for redacting or removing this information. Application deadline: Amgen does not have a fixed deadline; we will continue accepting applications until we select a candidate. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will provide reasonable accommodations to participate in the job application or interview process. Please contact us to request accommodation. Seniority level Mid-Senior level Employment type Full-time Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at BioSpace. Get notified about new Principal Scientist jobs in Thousand Oaks, CA. 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Created: 2025-10-06