Senior Principal Scientist, Precision Medicine, ...

OverviewSenior Principal Scientist, Precision Medicine, ImmunologyPrecision Medicine is an integral part of our Immunology Therapeutic Area. We are seeking an experienced experimental medicine leader in the newly created Precision Medicine and Diagnostics function to support our growing Immunology pipeline across Gastroenterology, Rheumatology and Dermatology. This role reports to the Associate Vice President, Precision Medicine and Diagnostics and serves as the translational lead on late-stage immunology programs, driving the Precision Medicine objectives in alignment with clinical development plans. You will collaborate with Discovery, Translational Medicine and Product Development Teams to define and interpret translational experiments and data generated from clinical trials, and understand the potential clinical applications of biomarkers/diagnostics arising from these efforts.ResponsibilitiesWork with the Associate Vice President Precision Medicine and Diagnostics/TA Vice President and cross-functional partners to define Precision Medicine strategy within the Immunology TACollaborate with a cross-functional group of experts, including clinical directors, clinical trial operations, and biomarker operations teams as their key liaison to enable implementation of precision medicine strategy in clinical trialsContribute to creation of translational plans for all programs within the Immunology TA, aligned with overall TA strategy and with relevant disease area and/or pathway strategiesCollaborate with discovery colleagues for programs in early stage to influence biomarker assessments and readouts to drive forward and reverse translation tied to Precision Medicine goalsChampion the use of new technologies and modalities to drive Precision Medicine visionSupport the development, approval and commercialization of diagnostics developed as companion or complementaryServe as the key stakeholder engaging with external experts on drafting and reviewing concepts aligned with Precision Medicine goals for relevant programs/assetsResponsibilities – Scientific KnowledgeMaintain awareness of scientific developments within one’s area of expertise, including new findings and research methodologiesAttend appropriate scientific meetings to maintain competency and awareness of related research activitiesAdditional ActivitiesAuthor detailed development documents, presentations, budgets, and position papers for internal and external audiencesCollaborate with external experts/researchers with expertise related to Precision MedicineTravel on company business about twenty percent of the time to manage future or ongoing clinical research projectsRequired QualificationsPhD degree in ImmunologyMinimum of 8 years of experience in immunology translational research in pharmaceutical and academic settings, focusing on inflammatory and autoimmune diseases in Gastroenterology, Rheumatology, and DermatologyStrong knowledge of the pathogenesis of immune-mediated disease and the application of cellular, molecular technologies and models to drive program decisionsDetailed understanding of translational and clinical research methodology and biostatistics principlesPrior experience in drafting regulatory documents and interactions with global regulatory agenciesSelf-driven leader willing to advance Precision Medicine in ImmunologyDemonstrated ability to work in a highly matrixed environmentPreferred QualificationsPeople management experienceEqual Employment Opportunity and AccessibilityAs an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. We are committed to inclusion and comply with applicable laws and regulations. For accommodation requests during the application or hiring process, please contact our team. #J-18808-Ljbffr

Created: 2025-10-06