Director Commercial Strategy, Iza-Bren

This role will report to the Executive Director, Commercial Strategy.As the Director Commercial Strategy, Iza-Bren, you will be responsible for development, implementation and management of commercialization strategy for iza-bren, a first-in-class EGFR-HER3 bi-specific antibody drug conjugate being developed under a collaboration agreement with BMS. This role will drive cross-functional alignment across commercial, clinical, regulatory, alliance management functions within SystImmune and is critical in ensuring SystImmune’s vision for Iza-Bren is represented throughout all strategic and operational discussions with BMS.This is an ideal role for a hands-on commercial leader with expertise in market analysis, forecasting, competitive intelligence, and cross-functional execution in oncology.Key Responsibilities:Commercial Execution for Izalontamab-BrengitecanLead the development and execution of the commercialization strategy for Iza-Bren, ensuring alignment across SystImmune and alliance partner BMSOwn day-to-day commercial planning, including target product profile (TPP) refinement, competitive positioning, and market readiness activitiesWork closely with clinical development teams (internal and alliance) to incorporate commercial insights into trial design and lifecycle planningCo-create and support execution of medical advisory boards and thought leader engagements (TLEs) to ensure external perspectives inform strategyMarket & Competitive Insights, Forecasting, and Commercial AnalyticsConduct market research and landscape assessments to refine patient segmentation, uptake drivers, and barriersDevelop a competitive intelligence framework, monitoring key ADC competitors and identifying implications for brand strategyWork closely with Finance and Business Development to develop and maintain revenue forecasts, ensuring alignment across internal and Alliance teamsAssess pricing and market dynamics, leveraging epidemiology data, analogs, and external insights to refine commercialization plansMap out and prioritize key performance indicators (KPIs) for market readiness and stakeholder engagement, ensuring SystImmune’s strategic priorities are representedCross-Functional & Alliance Collaboration for Market PreparationWork closely with Medical Affairs, Regulatory, Market Access, and other key functions (both internal and Alliance) to align commercialization effortsEnsure SystImmune’s vision is recognized in all Alliance discussions and decision-making across commercial, clinical, and medical affairs teamsSupport early-stage launch readiness planning, including defining key priorities for stakeholder engagement and market preparation effortsPartner with Alliance teams to ensure cohesive strategic messaging, commercial positioning, and cross-functional coordinationQualifications:Advanced degree (MBA, PharmD, PhD, or equivalent) in business, life sciences, or a related field7+ years of related experience in biotech/pharmaceutical and/or life sciences consulting roles, including commercial strategy, forecasting, market research, brand planning, or portfolio managementProven ability to collaborate across multiple functions, including clinical development, regulatory, medical affairs, finance, and market access, to align on commercialization strategiesStrong ability to analyze complex data and translate insights into strategic recommendationsExcellent communication and presentation skills across a variety of organization levels and functions including senior executivesAbility to influence and build effective relationships both within the organization and externally with alliance partners to drive projects and tasks towards completionPrior experience in ADCs is a plus but not required; experience in oncology and/or specialty pharmaceuticals preferredExperience working in an alliance or partnership setting is a plusThe hiring pay range for this position is $180,000 - $250,000 per year based on skills, education, and experience relevant to the role.SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery or IND-enabling stages, representing cutting-edge biologics development.We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package.SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. #J-18808-Ljbffr

Created: 2025-10-06