Toxicologist II with cell culture and DMPK experience

Job Title:Toxicologist II with cell culture and DMPK experienceJob Number: 101952Location: Atlanta,USJob DescriptionDescription:The Screening and Assay Development group seeks two graduates (MS or higher) in Toxicology, Toxicological Sciences or a related discipline, with experience in cell-based assays and HTS. The primary responsibility will be to conduct chemical testing and interpret PK data and mechanism-informing toxicity data from the in vitro assays. The preferred candidate would have extensive experience with high-throughput screening (HTS), ADME/drug metabolism enzyme (DME) assays, solid understanding of biochemical pathways and enzyme kinetics, and expert knowledge of cell culture. Experience with microsomal DME assays and vesicle-based transporter assays is a plus, but not required.Qualifications:• Hands-on experience with cell-based toxicity assays• Ability to interpret pharmacokinetic data from in vitro studies• Knowledge of major DMEs (CYP450s, UGTs, etc.) and transporters• Ability to apply biochemical principles to drug metabolism and toxicology• Proficiency in cell culture techniques (e.g., cell maintenance, passaging, differentiation etc.)• Experience with primary cells, iPSCs and cell lines• Proficiency in standard laboratory techniques and HTS• Experience with data analysis and statistical computation (R or GraphPad Prism, Python)• Ability to execute, troubleshoot and analyze experiments and to interpret results• Familiarity or experience with machine learning• Documentation of procedures and results in compliance with Electronic Lab Notebook guidelines• Strong interpersonal and organizational skills• Ability to work in a fast-paced environment• Excellent oral, written and presentation skills• Willingness to travel and present at conferences• MS or PhD in a relevant scientific disciplineEmployment requirements:•At least three references.•Successfully completed background check.Confidentiality:Your information will be kept confidential according to EEO guidelines.Application Deadline: 2025-10-31 #J-18808-Ljbffr

Created: 2025-10-08