IT Operations Manager

Job Summary: Lead and build a U.S.-based IT organization supporting the San Diego and North Carolina sites, ensuring robust data security, privacy compliance, and regulatory alignment. Oversee enterprise IT infrastructure, cloud platforms (AWS/Azure), NGS systems, laboratory technology support, data management, and cybersecurity governance. Establish and maintain clear operational and administrative separation between U.S./EU and China IT environments to safeguard data integrity and compliance. Responsibilities: IT Operations & Infrastructure • Oversee daily IT operations for San Diego and North Carolina sites including user support, incident management, and service delivery • Manage cloud infrastructure: AWS (EC2, S3, RDS, Lambda, IAM) and Azure (VMs, Storage, AD, Monitor) • Maintain on-premises data center, NGS infrastructure, bioinformatics systems, servers, storage, and network equipment • Support laboratory equipment connectivity, scientific software, and instrument data management Data Management & Security • Implement data backup, recovery, encryption, and access controls; maintain retention policies • Ensure EO14117 compliance: IAM policies, privileged access management, China/US separation, network segmentation • Conduct security assessments, maintain audit readiness, and respond to incidents Team & Budget Management • Build and manage US IT team; provide mentorship and performance management • Manage vendor relationships, contracts, and IT operations budget Minimum Requirements: • Bachelor's degree in Computer Science, Information Technology, or a related field required • 7+ years of progressive experience in IT operations management • 3+ years of hands-on experience managing cloud environments (AWS and/or Azure) • 1+ year of people leadership experience, including team development and oversight • Experience operating within regulated industries and U.S. government compliance frameworks (e.g., EO 14117, FedRAMP, or similar) • Cloud: AWS (EC2, S3, RDS, Lambda, IAM), Azure (VMs, Storage, AD) • Systems: Windows Server, Linux (RHEL/Ubuntu), VMware/Hyper-V • Network & Security: Firewalls, VPN, IAM, Active Directory, MFA, SIEM • Scripting: PowerShell, Python, Bash • Tools: ITSM (ServiceNow/JIRA), monitoring (CloudWatch/Azure Monitor) • Specialized: NGS infrastructure, LIMS, bioinformatics, compliance (HIPAA, SOC2, ISO27001) Other Requirements • 10-20% travel between sites; on-call availability (24/7) • Strong communication skills; ability to explain technical concepts to non-technical stakeholders Work Authorization Requirement: This position requires U.S. Citizenship or U.S. Permanent Residency (Green Card) due to compliance with Executive Order 14117 and applicable U.S. government data security regulations. Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

Created: 2026-03-04