Vice President, Clinical Operations, US

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. Why Join Us? Innovative Environment: Help to pioneer advancements in cancer immunotherapy. Collaborative Culture: Be part of a diverse team dedicated to your professional growth. Global Impact: Contribute to therapies that make a lasting impact on patients globally. We are seeking a Vice President, Clinical Operations, US to support our US Clinical Operations Department. FLSA Classification: Salary, Exempt Schedule: Full Time, Business Hours of 8:00 am - 5:00 pm, Monday to Friday Reports to: Senior VP, Clinical Development Location: Fully Remote What You'll Do: As a Vice President, Clinical Operations, US, you will play a key role in supporting our clinical operations department: Main responsibilities of this position will include but are not limited to the following tasks: Provide strategy and operational leadership for Clinical Operations activities focusing on site management and systems Build, lead and inspire a high-performing Clinical Operations department within the scope of responsibilities Ensure timely and high-quality execution of clinical trials related to agreed timelines, budget, GCP compliance and quality Resource, budget Planning and Controlling Clinical Operations within the scope of activities Liaises with the VP Clinical Operations, Germany on budget planning, Contribute to the global clinical development strategy in close collaboration with global cross-functional stakeholders Identify and mitigate operational risks proactively With the EU counterpart, implement scalable processes and systems that support growth and adaptability Champion innovation in clinical trial execution, including emerging tools and agile methodologies Required Experience and Education: Min. Master's Degree, preferably in life science or nursing; or equivalent At least 8 years of Clinical Operations experience in the pharmaceutical/ biotechnology industry (mainly in clinical project management and group/department leadership), preferred in oncology and cell therapy At least 4 years line management experience Elevated level of individual responsibility, enthusiasm Strong team player Excellent verbal and written communication skills in English Analytical reasoning and deep project management skills Independent, structured, reliable, resilient and foresighted working style Ability to prioritize and adapt quickly in a fast-paced and changing industry. Strategic thinker within Clinical Operations and beyond Proactively drive company standards and global harmonization in the Clinical Operations area Proactively drive quality and efficiency to meet timelines and milestones to deliver high quality clinical trial deliverables. Open minded for rapidly changing requirements Outside the box thinking and a high degree of flexibility in an environment which is marked by a constant striving for excellence Preferred Experience and Education: Intermediate Excel skills. Professional writing experience. Competencies: Initiative Problem Solving Proactivity Work Environment: The VP of Clinical Operations will operate in a remote work environment with regular virtual collaboration across global cross-functional teams. The role requires a high degree of self-direction, proactive communication, and the ability to lead and manage clinical teams across time zones. Occasional travel may be required for key meetings, site visits, or strategic planning sessions. A strong digital presence and comfort with remote leadership tools are essential for success in this role. Travel required: up to 10%-20% travel required, domestically and internationally. Physical demands: Communicating Verbally - expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly. Hearing - the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds. Keyboarding - entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others. Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object - usually by holding it in the hands or arms but may occur on the shoulder. Near Visual Acuity - clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers). Pushing - Exerting force upon an object so that the object moves away from the object. Pulling - Exerting force upon an object so that the object moves toward the force. Sitting - remaining in a sitting position for at least 50% of the time. Standing/Walking - remain on one's feet in an upright position at a workstation. Stooping - occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles. Work authorization/security clearance requirements: Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment. Affirmative Action/EEO statement: Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, national origin, ethnicity, marital status, age, physical or mental disability, medical conditions, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. What do we offer? At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics Comprehensive Benefits: Competitive rates for Health, Dental, and Vision Insurance 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment. Sick Time Off - 56 hours 12 Paid Holidays 100% Employer-Paid Life Insurance up to at 1x annual salary 100% Employer Paid Short- and Long-Term Disability Coverage 401(k) with Immediate Eligibility & company match... You are eligible for 401(k) plan participation as of your first paycheck. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. Partially paid Parental Leave for eligible employees. (3 weeks) Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance. Professional Growth: Opportunities to work with leading experts in the field of T-cell immunotherapy. Company provided learning and development opportunities Fast paced, high demand collaborative and dynamic environment.

Created: 2026-03-04