Senior Director, Medical Affairs Research, Oncology

Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook. The Senior Director, Medical Affairs Research (MAR), Oncology is a senior leadership role responsible for catalyzing and advancing Guardant Health's Research strategy in oncology through engagement with leading oncology experts and academic institutions to deliver on research and publication strategy. This role leads, mentors, and manages a team of U.S.-based Medical Affairs Research professionals, driving field-based scientific engagement, clinical education and investigator-initiated studies. The Senior Director serves as a key cross-functional leader, working in partnership with external experts and internal stakeholders across clinical development, Publications, technology development and marketing teams. This position ensures high scientific rigor and impactful dissemination of data to advance Guardant Health's oncology portfolio and pipeline, while elevating the company's scientific credibility and academic footprint within the U.S. oncology community. Essential Duties and Responsibilities: Lead, mentor, and manage the Medical Affairs Research Oncology team to establish and maintain relationships with Clinical and research oncology experts for scientific exchange and research collaboration, elevating Guardant Health's impact and scientific rigor within the US. Foster a collaborative, high-performance team environment; identify and prioritize key scientific and clinical areas of focus for the Medical Affairs Research team to prioritize and deliver. Set clear goals and objectives for team members, monitor progress, provide regular feedback and actively participate in co-travel and/or observation with each Medical Affairs Research team member to oversee in-field research activity. Develop and implement strategy for MARs deployment, aligning external medical research activities with broader organizational goals and medical and clinical development strategies. Create institutional research plans for academic and key accounts in collaboration with Key Accounts team and cross functional field leadership. Facilitate scientific discussions and exchange of information on Guardant Health's products and pipeline and latest advancements in oncology precision medicine with top opinion leaders and research partners. Define best practices nationwide to streamline inbound research requests from additional US Medical Affairs partners to promote deeper understanding of Guardant research practices and strategies and expand academic footprint. Catalyze the advancement of research alongside collaborators to deliver on data and publication plans and provide input into strategic data generation plans. Champion effective scientific writing for effective data submissions to peer-reviewed journals and top global oncology conferences; Assesses, contributes and coaches to improve quality of peer-reviewed research. Ensure compliance with regulatory standards and internal policies in all activities. Serve as cross-functional lead for collaboration with clinical development, regulatory, marketing, and commercial teams to support product development with respect to top KOL feedback and data generation planning. Oversee the development and dissemination of pipeline scientific and medical content, including presentations, publications, and educational materials. Ensure all communications are accurate, balanced, and supported by data. Oversee the collection and analysis of field-based medical insights from top opinion leaders to inform strategic decisions. Prepare regular reports and presentations on Medical Affairs Research, Oncology team activities, impact, and outcomes. Provide content input and review for external-facing company developed materials (Clinical, Medical, and Commercial). Required Qualifications: Typically requires a university degree and generally 12 years of related experience; 12 years and a Master's degree; 8 years and a PhD; or 5 years and a PharmD/MD. Extensive experience in oncology and genomics is required. History of acceptances of high-quality peer-reviewed abstracts and publications in the oncology setting. Ability to tailor communication for diverse audiences, including team members and senior executives. Proven track record of leading and managing field-based medical teams with strong leadership, team management, and communication skills. Skilled in developing and executing strategic plans with strong organizational and project management expertise. Proficiency in data analysis and interpretation. Knowledge of regulatory standards and industry guidelines. Expected in field travel up to 50% with attendance to conferences, offsites and quarterly field rides with all direct reports. Work Environment: Moderate travel required, approximately 3-5 trips per quarter to meet with KOLs/PIs, attend conferences, including specialty society scientific meetings (will require some weekend work), and trips to headquarters. Travel is estimated to be up to 50%. Ability to travel frequently by car, plane, and other forms of public transportation, with or without reasonable accommodation. Office may be home-based and involve extensive use of computers and keyboards while in the home office. Requires the ability to focus on multiple tasks simultaneously, work in a fast-paced, high-energy environment, and the ability to work independently and remotely while maintaining a strong teamwork ethic. Hybrid Work Model:This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients. The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate's compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.Primary Location: Palo Alto, CAPrimary Location Base Pay Range: $294,600 - $405,050Other US Location(s) Base Pay Range: $294,600 - $405,050If the role is performed in Colorado, the pay range for this job is: $294,600 - $405,050 Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952). Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Please visit our career page at:

Created: 2026-03-04