Site MS&T Head, SMO

Job Description Summary #LI-Onsite Location: Morrisville, NC The Site, Manufacturing, Science & Technology Head - Small Molecule is an Associate Director level role. You will lead the Manufacturing Science and Technology (MS&T) organization, ensuring our products remain in a state of control through deep product knowledge, process understanding, and the application of technology. Your focus will be on driving continuous improvement while reducing process variability and waste. You will drive endtoend product and process stewardship across the lifecycle, strengthening validation activities, launches, and technical transfers, and ensuring inspection-readiness through standardization, sustainability, innovation, and technology-ultimately enabling patient safety and reliable supply. By partnering across functions and the global MS&T network, you will accelerate the adoption of best practices, advance Quality by Design, Design of Experiments, and Process Analytical Technology, and build the capabilities needed to shape the future of operations. If you're energized by leading experts, influencing strategy, and making a direct impact on how patients receive highquality therapies, this role offers a powerful platform. Job Description Key Responsibilities: Define MS&T vision, technical standards, and strategic priorities that strengthen site performance and scientific capability. Act asprimaryliaison with site leadership and global platform heads to alignobjectivesand resolve technical issues. Builddepartmenttechnicalexpertiseby overseeing career paths, succession plans, training programs, and crossfunctional knowledge management. Ensureinspectionreadiness and drive rapid reapplication of global best practices, standard processes, and compliance improvements. Lead endtoend productand process stewardship tomaintainrobust, wellcontrolled manufacturing throughout the lifecycle. Oversee technical change control and serve as site interface for regulatory interactions and submission content. Own the Validation Master Plan and ensure execution, monitoring, and continuous verification of validated processes. Direct technical transfers, launches, and scaleups, ensuring strong project leadership and seamless execution. Advance manufacturing excellence by applying Quality by Design, Design of Experiments, and Process Analytical Technology. GuideTechnology Life Cycle Management,new technologyadoption, and ensure technical inputs shape capital project decisions. Essential Requirements: Bachelor's Degree Required.Master's degree in Science, Pharmacy, Chemical Engineering, Pharmaceutical Technology, or equivalent scientific disciplinepreferred. Minimum10 years ofworkexperiencewithin the pharmaceutical industry.Extensiveexperience in manufacturing operations, including product, process, or technology oversight. Demonstrated ability to drive quality, compliance, and continuous improvement in a regulated environment. Strong understanding of applied statistics, quality systems, and regulatory requirements across multiple health authorities. Proven capability in process development, technical problemsolving, and lifecycle stewardship of commercial products. Working knowledge of pharmaceutical analytical testing and its application to process and product understanding. Experience leading technical teams, developing talent, and building organizational capabilities. Strong ability to collaborate across functions and influence decisionmaking at multiple organizational levels. Desirable Requirements: Diverse pharmaceutical experience needed. Specifically, Small Molecule DS (API/DrugSubstance/Oligonucleotide)/ Small Molecule DP/FP (Drug Product/Finished Product) is highly preferred. Novartis Compensation and Benefit Summary:The salary for this position is expected to range between $138,600 and $257,400 per year. The final salary offered isdeterminedbased on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health,lifeand disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days,holidaysand other leaves. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $138,600.00 - $257,400.00 Skills Desired Applied Statistics, Data Analytics and Digital, GDP Knowledge, gmp knowledge, HSE Knowledge, Leadership, Manufacturing Process, Manufacturing Production, Manufacturing Technologies, Operational Excellence, Process and Cleaning Validation, Process Control, Quality Compliance, Regulatory Compliance, Resilience and Risk Management, Resource Planning and Forecasting, Technical Leadership, Technology Transfer

Created: 2026-03-10