Clinical Research Nurse Manager

Essential Functions Direct and oversee daily clinical research nursing activities from protocol feasibility and study start-up through study close-out, ensuring scientific integrity and quality under the supervision of the Principal Investigator (PI) and in collaboration with the assigned medical leadership. Provide operational leadership for the research nursing team, overseeing daily workflow, clinical coverage, and department functions. Assess staffing requirements, coordinate schedules, and ensure adequate clinical coverage to support research activities. Promote and enforce compliance with clinical, regulatory, and research-related standard operating procedures (SOPs). Support adherence to protocol-specific manuals and SOPs by planning, delivering, and evaluating protocol orientations and ongoing education for research and clinical staff; implement workflow or process improvements as needed. Lead staff meetings, educational sessions, and competency-based training programs. Complete performance evaluations for direct reports and recommend corrective or disciplinary actions when appropriate. Define and assign responsibilities for complex research protocols to reduce protocol deviations and minimize unanticipated events. Provide leadership and subject matter expertise in the development, implementation, and execution of regulatory and clinical strategies supporting research initiatives. Supervise and guide direct reports responsible for coordinating patient participation across all study phases, including consent, screening, treatment, and follow-up. Ensure accurate, timely identification, documentation, and reporting of adverse events in accordance with institutional policies, sponsor requirements, and regulatory timelines. Oversee and support clinical procedures performed by research nursing staff, including vital signs, laboratory collections, electrocardiograms (EKGs), and other protocol-required assessments. Partner with research leadership and managers to support staff management, resource planning, performance monitoring, and compliance oversight across multiple clinical research programs. Maintain effective communication and collaboration with internal teams, external partners, sponsors, investigators, and study participants. Review and assess proposed research protocols to determine feasibility, staffing needs, and resource requirements. Assist in the selection, development, and implementation of clinical research technology platforms and supporting infrastructure. Develop protocol-specific needs assessments and oversee quality assurance processes related to clinical research services. Prepare for, participate in, and support sponsor, institutional, and regulatory audits and inspections. Provide direct nursing care to research participants as needed, including administration of investigational agents, patient assessments, and monitoring during clinical visits, ensuring strict adherence to protocol requirements. Ensure all clinical research activities comply with Good Clinical Practice (GCP), federal regulations, sponsor guidelines, and institutional policies. Travel to research sites as required to support study operations and staff oversight. Maintain professionalism, patient confidentiality, and ethical standards in all interactions. Demonstrate reliable attendance, punctuality, and a professional demeanor and appearance. Maintain active nursing licensure as required by the role. Perform additional duties as assigned to support research operations and organizational objectives. Required Skills Excellent verbal and written communication skills. Strong organizational and follow-up skills. Ability to handle multiple priorities in a fast-paced environment. Understanding complex clinical trials protocols. Ability to direct, manage, implement, and evaluate department operations. Ability to establish department goals, and objectives that support strategic plan. Effective planning, delegation, and supervision skills. Ability to travel up to 25% (local/regional). Proficiency in Microsoft Office products (Word, Excel, PowerPoint, etc.) Knowledge of protocol and clinical drug development processes, study design, study planning andmanagement, and monitoring. Knowledge of ICH/GCP guidelines Associate in nursing or Bachelor's in nursing required. Current Tennessee RN license 5+ years of experience as registered nurse 3+ years of experience in oncology setting Previous clinical research experience required, oncology research preferred. Previous supervisory and/or management experience, preferred Preferred Skills Oncology Research Experience in Management Schedule/Shift Monday-Friday 8am-5pm, but must be flexible as Manager to step in where needed if after or before hours We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable federal, state, and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance (FCIHO), Los Angeles Fair Chance Ordinance for Employers (ULAC), The San Francisco Fair Chance Ordinance (FCO), and the California Fair Chance Act (CFCA). As a job position within our Clinical Sciences division, a successful completion of a background check may be required as a condition of employment. This requirement is directly related to essential job functions including but not limited to: high-risk working environments (laboratories, clinical settings), handling hazards chemicals or lab specimens, conducting direct patient care, accessing medical and confidential records, access to prescription medication or other drugs, and job duties that can cause serious injury or death as a result of error. Due to these job duties, this position has a significant impact on the business operations and reputation, as well as the safety and well-being of individuals who may be cared for as part of the job position or who may interact with staff or clients.

Created: 2026-03-10