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Research Scientist

Actalent - Cambridge, MA

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Job Description

Computational Scientist - AI/ML for Antibody & Biologic Design (Remote‑Eligible) We are seeking a highly skilled Computational Scientist to help advance next‑generation antibody and biologic discovery using cutting‑edge AI/ML methods. In this role, you will apply machine learning, deep learning, and generative modeling to protein, antibody, and oligonucleotide design. You will collaborate closely with research teams to build models that accelerate discovery across modalities including antibodies, siRNA, PMOs, and conjugates. Key Responsibilities + Develop and apply AI/ML and generative modeling approaches to enable novel antibody and protein designs. + Support multiple biologic modalities-including antibodies, siRNA, PMOs, and conjugates-using predictive and generative ML tools. + Build, train, and optimize machine learning models for DNA, RNA, and protein sequence‑to‑function predictions. + Contribute to model architecture selection, dataset curation, and workflow development for biologics discovery. + Collaborate with cross-disciplinary scientists to integrate computational outputs into experimental pipelines. + Present findings, document methodologies, and support ongoing platform development. Required Qualifications + PhD in Computational Chemistry, Computational Biology, Chemical Engineering, or a related discipline. + 2-3 years of experience in antibody design, characterization, or oligonucleotide chemistry. + Strong understanding of deep learning architectures, including RNNs, GNNs, and generative AI frameworks. + Demonstrated experience applying ML techniques to DNA, RNA, and protein datasets. + Ability to work independently in a fast-paced research environment while contributing to collaborative team goals. Preferred Skills + Experience with protein engineering, molecular modeling, and sequence‑based ML. + Familiarity with antibody discovery workflows and biologics R&D. + Hands‑on experience with Python ML frameworks (e.g., PyTorch, TensorFlow). + Strong communication skills and ability to translate computational insights for wet‑lab partners. Work Schedule & Location + Remote candidates are welcome. + Ideal candidates are located within 1 hour of Cambridge, MA for occasional onsite meetings and team collaboration. If interested, please reach out directly to Lindsee Allienello at lallienello @ . Job Type & Location This is a Contract position based out of Cambridge, MA. Pay and Benefits The pay range for this position is $51.00 - $58.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: - Medical, dental & vision - Critical Illness, Accident, and Hospital - 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available - Life Insurance (Voluntary Life & AD&D for the employee and dependents) - Short and long-term disability - Health Spending Account (HSA) - Transportation benefits - Employee Assistance Program - Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully remote position. Application Deadline This position is anticipated to close on Apr 17, 2026. Diversity, Equity & Inclusion At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I is embedded into our culture through: + Hiring diverse talent + Maintaining an inclusive environment through persistent self-reflection + Building a culture of care, engagement, and recognition with clear outcomes + Ensuring growth opportunities for our people Actalent is an equal opportunity employer. About Actalent Actalent is a global leader in engineering and sciences services. For more than 40 years, we've helped visionary companies advance their goals. Headquartered in the United States, our teams span 150 offices across North America, EMEA, and APAC-with four delivery centers in India led by 1,000+ extraordinary employees who connect their passion with purpose every day. Our Bangalore, Hyderabad, Pune, and Chennai delivery centers are hubs of engineering expertise, with core capabilities in mechanical and electrical engineering, systems and software, and manufacturing engineering. Our teams deliver work across multiple industries including transportation, consumer and industrial products, and life sciences. We serve more than 4,500 clients, including many Fortune 500 brands. Learn more about how we can work together at .

Created: 2026-04-19

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