Postdoctoral Fellow - Therapeutic Senescence & Tumor ...

$72,000 to $113,900The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe.Please review important announcements about vaccination requirements and our upcoming EHR implementation by clicking here.Exciting Opportunity at MSK: The Romesser Lab is looking for a Postdoctoral Fellow to join our team studying therapy induced senescence and tumor immunology.Role OverviewDr.PaulRomesser’s laboratory is recruiting abold and innovativePostdoctoral Fellowtoturn cellular senescence into a weaponized immunologic state against cancer. Rooted in rectal cancer—but engineered to translate across immune"‘refractory tumors—our program fusesimmunocompetent mouse models, patient"‘derived organoids, single"‘cell/spatial multi"‘omics, and CRISPR"‘based functional genomics. You willdrive NIH"‘ and foundation"‘funded projectsthat dissect the senescence-immune interface and fast"‘track novel combination therapies toward first"‘in"‘human trials, all within MSK’s collaborative, technology"‘rich ecosystem.Key Requirements:PhD or MD/PhDin Cancer Biology, Immunology, Molecular Biology, or a related disciplineHands on expertise in at least one of the following:Immunocompetentmouse tumor modelsPatient"‘derived organoidculture and manipulationFlow cytometry or advanced immune-profiling platformsSingle"‘cell or spatial omics Computational proficiency—familiarity with R/Python for analysis of bulk, single"‘cell, or spatial"‘omics data (or a strong willingness to learn).Strong publication recordthat highlights independent thinking and problem"‘solving.Excellent communication skills(written and oral) and a track record of productive collaboration within interdisciplinary teams.Core Skills:Experimental Design & Troubleshooting: Ability to conceptualize, execute, and optimize complex invivo (mouse) and exvivo (organoid) studies, including CRISPR perturbations and multiplex assays.Single"‘Cell & Spatial Multi"‘omics: Competence in generating and/or analyzing scRNA"‘seq and spatial transcriptomics data; comfortable using pipelines such as Seurat, Scanpy, or equivalent.Data Analysis & Visualization: Fluency in R/Python for statistics, data integration, and production"‘quality figures that clearly communicate findings to diverse audiences.Immunological Assays: Proficiency with flow cytometry, ELISA/LEGENDplex, functional T"‘cell or myeloid assays, and lymphoid and myeloid co-culture assays for dissecting tumor-immune interactions.Scientific Communication & Leadership: Strong track record of manuscript preparation, conference presentations, and collaborative project management; ability to mentor junior trainees and foster an inclusive lab culture.Application Instruction: Submit C.V., letter of interest, and references in your application submission to: Contact Name: Tiara Williamson Contact Email: : $72,000 to $113,900Learn more about working as a Post-Doctoral at MSK: Discover MSK’s world"‘class core facilities, multidisciplinary mentorship, and robust career"‘development programs atAs a fellow, you’ll leverage cutting"‘edge technologies—ranging from single"‘cell and spatial"‘omics platforms to premier animal and organoid cores—while collaborating across oncology, immunology, and computational biology. This uniquely collaborative ecosystem accelerates transformative science into therapies that improve patient outcomes worldwide.Helpful links:MSK Compensation PhilosophyReview Our Great Benefits OfferingsMSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Created: 2025-06-14