Postdoctoral Fellow-MSH

Job Description _Roles & Responsibilities:_ The Gregorio Lab in the Cardiovascular Research Institute (CVRI) at the Icahn School of Medicine at Mount Sinai is seeking highly motivated candidates for the full-time position of Postdoctoral Research Associate I. Dr. Gregoriou2019s NIH-funded research incorporates molecular, cellular and physiological approaches on the RNA/protein level to identify molecular mechanisms that underlie contractile protein function in heart and skeletal muscle diseases. Current studies focus on the role of RNA-binding proteins in muscle function that are altered during normal development and in disease such as Duchenne Muscular Dystrophy. The laboratory generates, analyzes, and integrates high-throughput fluorescence imaging, molecular biology and biochemistry to determine the mechanism of RNA binding proteins in cells (e.g., iPSCs, primary myocytes) and animal models that reflect patho/physiological states. The successful Postdoctoral candidate will possess a cell/molecular skill set with an emphasis on RNA biology appropriate to accomplish the labu2019s goals. In addition, they will possess the drive required to research complex disease and will be able to work independently as well as collaboratively. CVRI is dedicated to training the next generation of scientists, and the Postdoctoral candidate will benefit from the interdisciplinary environment. Duties: u00b7 Lead a research project in close collaboration with the PI and other lab members. u00b7 Innovate new areas of experimental inquiry. u00b7 Advance technical aspects of experimental approaches and mechanistic understanding of biological problem. u00b7 Mentor junior lab members and contribute to a productive scientific environment. u00b7 Maintain detailed records and disseminate research findings in meetings and as manuscripts in scientific journals: strong writing skills are essential u00b7 Apply for independent funding and contribute to grant proposals submitted by the PI. u00b7 There may be additional duties assigned as it relates to this position. _Requirements:_ Minimum Requirements: u00b7 MD or PhD in biochemistry, molecular or cellular biology, physiology, biotechnology, biomedical engineering, or related field by time of hire. u00b7 Documented ability to conduct original research. u00b7 Ability to write manuscripts and grants proposals. u00b7 Ability to work with small animals. Preferred Qualifications: Experience with recombinant proteins, muscle proteins, and handling/dissection of small rodents. Experience with enzyme kinetics/biochemical assays of protein-protein interactions. Experience with fluorescence microscopy. Experience with Duchenne Muscular Dystrophy Models. Expertise in cardiac and skeletal muscle biology, post-transcriptional and translational regulation in heart and skeletal muscle disease pathology. Experience in computational biology. Qualifications . Responsibilities . About Us Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinaiu2019s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. About the Mount Sinai Health System: Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time u2014 discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patientsu2019 medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high

Created: 2025-11-15