Lead Production Chemist

JOB REQUIREMENTS: Work Your Magic with us Start your next chapter andjoin MilliporeSigma. Ready to explore, break barriers, and discovermore? We know you've got big plans - so do we Our colleagues acrossthe globe love innovating with science and technology to enrichpeople's lives with our solutions in Healthcare, Life Science, andElectronics. Together, we dream big and are passionate about caring forour rich mix of people, customers, patients, and planet. That's why weare always looking for curious minds that see themselves imagining theunimaginable with us. This role does not offer sponsorship for workauthorization. External applicants must be eligible to work in the US.JOB SUMMARY For over 25 years, Mirus Bio pioneered the manufacture oftransfection reagents and proprietary technologies for nucleic aciddelivery applications. Despite our extensive experience, we prideourselves on maintaining the spirit of a startup. Our dynamic andforward-thinking approach has allowed us to stay agile and adapt toemerging trends. Our work is technical and cutting-edge, and we promotea culture that encourages creativity, initiative, responsibility, andrespect. Our team members are engaged and motivated by the desire tosupport our customers to practice good science to generate strongresults. Mirus, together with MilliporeSigma, is establishing the futureof science and medicine by developing products that enable researcherswithin the cell and gene therapy space. Mirus Bio is seeking a full-timeonsite Lead Production Chemist to synthesize critical compounds forMirus Bio's product portfolio including in vitro transfection reagents,nucleic acid labeling reagents, and accessory products. This individualcontributor position will take a Lead role for the Production ChemistryTeam. This is a divided role with approximately half of the time spentin the laboratory performing hands-on synthesis of Production Chemistrycompounds. The other half of the time will be spent as the SubjectMatter Expert who is also responsible for Raw Material Tech Transfer,flexing as required. This position will report to the ProductionManager. This role is a part of a dynamic and fast-paced environmentthat collaborates closely with Production, Quality, Product Management,Project Management, and R&D Departments in a small start-up styleenvironment. DUTIES & RESPONSIBILITIES Chemistry Subject MatterExpert (SME) who is responsible for the hands-on synthesis of lipids,polymers and small molecules for Mirus Bio products for both new productintroductions (NPIs) tech transfers and the existing Mirus Bio productportfolio, with extensive knowledge on synthesis scale up technologiesand techniques. Core Project Team Member for the technical transferof Chemistry Production to manufacturing partners. This includes beingresponsible for the process development at manufacturing partners andbeing the SME and Technical Owner of Raw Material GMP Processes andongoing oversight. Project Lead for the NPI raw material technicaltransfers from R&D to RUO Production Chemistry. Lead ProductionChemist owning, overseeing, and supporting multiple projects,manufacturing partner productions, RUO productions, and other activitiesin parallel. Adapts to changing priorities and works cross-functionallyto ensure on time deliverables and while ensuring a balanced workload. Technical support for the extensive characterization of compoundsusing various physical and chemical characterization techniques such gelpermeation chromatography (GPC), dynamic light scattering (DLS), nuclearmagnetic resonance spectroscopy (NMR), high performance liquidchromatography (HPLC), fluorescence, mass spectrometry (MS), infra-red APPLICATION INSTRUCTIONS: Apply Online:

Created: 2025-10-04