Rearch Professional 2
MSCCN - Minneapolis, MN
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Apply for Job Job ID371539 LocationTwin Cities Job FamilyResearch Full/Part TimeFull-Time Regular/TemporaryRegular Job Code8352GC Employee ClassCivil Service Add to Favorite Jobs Email this Job About the Job This position is in the lab of Dr. Frank Cichocki. Our lab focuses on the use generation and use of induced pluripotent stem-cell derived natural killer cells to study basic NK cell biology and to inform the development of clinical-grade NK cell therapies to target specific cancers. Applicants will be performing cell culture and differentiation of iPSCs, expansion of differentiated iPSC NK cells and maintenance and storage of feeders and terminally expanded cell products. This position is based on campus. Per UMN policy, work may be done remotely when appropriate and approved by your manager. All UMN employees are expected to follow applicable public health and safety procedures. This position is funded for 1 year. Responsibilities: Function 1 (40 %): Differentiation of iPSC to CD34+ cells This requires extensive knowledge of differentiation procedures and maintenance/quality control of OP9 feeder cells and custom formulated media as well as an understanding of the appropriate cell morphology and phenotype during differentiation. Function 2 (40 %): Expansion of CD34+ cells to terminally expanded iNK Differentiated cells are expanded using K562 feeders according to a strictly defined protocol. Expanding cell phenotype must be watched closely by flow cytometric analysis. Function 3 (20 %): Production and maintenance of feeder cell stocks Expansion and maintenance of feeder stocks are critical to this role. Feeder cell cultures must be continuously maintained to ensure sufficient stocks are available for all experiments. Cells also require irradiation and making frozen stocks consistent with internal protocols. Qualifications Required qualifications: -BA/BS degree in biology, genetics or related field plus at least two years of relevant experience, or a combination of education and relevant work experience to equal at least six years. -Experience differentiating and expanding iPSC derived immune cells -Proficiency in cell culture and flow cytometry -Sterile technique Preferred qualifications: -Previous experience in a research setting. -Attention to detail and ability to troubleshoot problems -Good communication and technical writing skills -FlowJo proficiency About the Department The Masonic Cancer Center (MCC) is an NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting-edge research opportunities; and outstanding advanced education. Pay and Benefits Pay Range: $45,000 - $48,000; depending on education/qualifications/experience Time Appointment: 100% Appointment Position Type:Civil-Service & Non-Faculty Labor Represented Staff Please visit the Office of Human Resources website for more information regarding benefit eligibility. The University offers a comprehensive benefits package that includes: Competitive wages, paid holidays, and generous time off Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program Low-cost medical, dental, and pharmacy plans Healthcare and dependent care flexible spending accounts University HSA contributions Disability and employer-paid life insurance Employee wellbeing program Excellent retirement plans with employer contribution Public Service Loan Forgiveness (PSLF) opportu ity Financial counseling services Employee Assistance Program with eight sessions of counseling at no cost Employee Transit Pass with free or reduced rates in the Twin Cities metro area How To Apply Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your
Created: 2025-12-22