Postdoctoral Fellow - Prajwal Rajappa Lab

Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through Cleveland Clinic Research. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.Our translational laboratory is dedicated to bridging the gap between bench and bedside by developing innovative cellular immunotherapies for children and young adults with gliomas and other CNS tumors. We are particularly focused on integrating personalized medicine and immunotherapy as an addition to the standard of care to improve survival and quality of life for our patients.Principal Investigator: Prajwal Rajappa, MD, MSCleveland Clinic Research Department: Center for Immunotherapy and ImmunoOncology/ Cancer SciencesLab Research Topics:Pediatric and Adolescent and Young Adult (AYA) brain cancerGlioma and Central nervous system (CNS) tumor and immune biologyInnate (myeloid) and adaptive immunity within the glioma immune microenvironmentPersonalized medicineCellular immunotherapyFor more information about the lab’s research, please contact Dr. Rajappa at Responsibilities:Independent project design with the goal of data generation, analysis, interpretation and manuscript preparationConduct translational research focused on Pediatric and Adolescent and Young Adult (AYA) Gliomas and Central Nervous System tumorsDesign and implement cellular immunotherapy strategies to prevent glioma progressionDevelop and evaluate personalized medicine approaches to complement standard of careLeverage unique human and mouse archival tissues to advance research and clinical impactEducation:PhD or MD/PhD requiredMD with relevant laboratory experience may substitute for PhDLanguages:English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa statusWork Experience:Previous experience in a research or academic setting. Graduate student experience meets this requirement.Scientific writing experienceAdditional Preferred Qualities:Strong background in cancer biology or tumor immunologyExperience with molecular biology techniques and mouse modeling (in-vivo handling and treatment studies in mouse tumor model systems)Experience with multi-parameter flow cytometry, myeloid, NK, and T cell-based assays for human and mouse samplesExperience working with the interpretation of next-generation sequencing dataStrong publication record in addition to excellent communication and teamwork skillsPhysical Requirements:Ability to perform work in a stationary position for extended periodsAbility to operate a computer and other office equipmentAbility to communicate and exchange accurate informationAbility to distinguish colorManual dexterity to handle specimens and repair equipmentAbility to lift and transport equipment or specimens weighing up to 20 poundsMay be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.Personal Protective Equipment:PPE per institutional requirements; may vary by laboratoryPreferred Application Materials:CVResearch statementReferences listAll application materials should be submitted directly via email to Prajwal Rajappa at : Postdoc, Research, LRI, Pediatric Oncology, CNS Tumors, Personalized Medicine, Immunotherapy, Glioma, Translational Research, Tumor Microenvironment, Myeloid based Therapy, Single-cell Sequencing, Neuro-oncology, Cancer Genomics, Precision Medicine, Immuno-oncology, Cell Therapy, Translational MedicinePay RangeMinimum Annual Salary: $31,200.00Maximum Annual Salary: $312,000.00The pay range displayed on this job posting reflects the anticipated range for new hires. A successful candidate’s actual compensation will be determined after taking factors into consideration such as the candidate’s work history, experience, skill set and education. The pay range displayed does not include any applicable pay practices (e.g., shift differentials, overtime, etc.). The pay range does not include the value of Cleveland Clinic’s benefits package (e.g., healthcare, dental and vision benefits, retirement savings account contributions, etc.).

Created: 2026-01-12