Statistician

Lumanity is dedicated to improving patient health by accelerating and optimizing access to medical advances. We partner with life sciences companies worldwide to:Generate robust evidencedemonstrating product valueTranslate science and datainto compelling product narrativesEnable strategic commercial decisionsthat position products for market successOur work spans three complementary areas:Strategy & Insights,Value, Access & Outcomes, andMedical Strategy & Communications.About the roleThePatient-Centered Outcomes (PCO)team at Lumanity is seeking aStatisticianto join our growing statistics group. This position can be based in theUS (preferred), with flexible working arrangements;UKorEUconsidered.We are looking for candidates with aproven track record in life sciences consultingand expertise in applying advanced statistical methods topatient-reported outcomes (PROs).In this role, you will:Design and execute statistical analyses for PRO data in standalone studiesConduct post-hoc analyses of clinical trial data to uncover additional value in study treatmentsTranslate complex statistical results into evidence that meets regulatory, clinical, and payer expectationsServe as a trusted advisor to clients and stakeholders on PRO statistical strategies within drug development pipelinesThis is acareer-growth opportunity, with the hiring title determined by experience. You will start by contributing statistical expertise under the guidance of senior leaders, progressing toindependently managing the full research pipeline, from study design through data analysis to final reporting.Core Job ResponsibilitiesScientific Leadership & Study ExecutionDesign studies using non-interventional data or devise statistical approaches to analyze PROs in interventional studies, enabling robust and meaningful insights.Experience also designing and analyzing Discrete Choice Experiments (DCE) and other stated-preference methodologies (e.g., Best-Worst Scaling, Conjoint Analysis) to quantify patient preferences and inform product development and market access strategies is sought, though not required for this job.Develop detailed statistical analysis plans, execute data analyses, interpret findings, and prepare clear, comprehensive reports.Conduct post-hoc analyses of clinical trial data to identify additional treatment benefits or insights related to PROs.Compile and author statistical sections of COA dossiers, integrating evidence to support regulatory and market access submissions.Maintain strong Sponsor relationships by delivering scientifically rigorous analyses designed to meet client and program needs, balancing methodological precision with practical decision-making.QualificationsEducation & Experience: Master’s degree or higher in Statistics or Biostatistics, with 3-5 years of experience in a life sciences consultancy.Statistical Expertise for PROs: Proficiency in methods tailored for skewed, bounded, longitudinal, and missing PRO data, including:Mixed Models for Repeated Measures (MMRM)Analysis of Covariance (ANCOVA)Logistic RegressionNon-parametric tests (e.g., Wilcoxon Rank-Sum)Multiple Imputation or likelihood-based methods for missing dataSensitivity analyses for post-hoc scenariosRegulatory Knowledge: Comprehensive familiarity with frameworks that guide statistical methods for PROs, including:FDA’s Patient-Focused Drug Development Guidance Series and disease-specific guidancesHTA Coordination Group JCA Dossier guidanceEMA’s Reflection Paper on patient experience dataICH E9(R1) Statistical Principles for Clinical Trials: Addendum on Estimands and Sensitivity AnalysisFDA’s 2017 draft guidance on Estimands in Clinical TrialsTechnical Skills:Proficiency in R, including packages for longitudinal and categorical data analysis, and the wider tidyverse suiteExperience working in a regulated programming environmentDocumentation & Reporting: Skilled in preparing statistical analysis plans and technical reports using standardized templates to ensure efficiency and consistency.Soft Skills:Exceptional written and verbal communication skills, with the ability to translate complex statistical concepts into clear, actionable insights for diverse audiencesStrong problem-solving abilities and adaptability in fast-paced environmentsSkilled in partnering with clients during high-stakes projects, balancing responsiveness with scientific rigorProven ability to collaborate respectfully and effectively within cross-functional, mixed-methods research teamsInnovation: Experience leveraging emerging AI tools to scale statistical programming and enhance scientific writing efficiency.We offer our employees a comprehensive benefits package that focuses on what matters to you - health and well-being, personal finances, professional development, and a healthy work/life balance:Competitive salary plus bonus schemeMedical, dental, and vision insurance options401(k) plan with employer matchGenerous amount of paid time off annually + 10 paid holidaysFlexible spending accounts for health and dependent careEmployee Assistance ProgramPaid short-term and long-term disability coverage and more#LI-Hybrid

Created: 2026-01-28