POSTDOCTORAL RESEARCH FELLOW (Miraldi) - Computational ...

Dr. Miraldi's Immuno-Engineering Laboratory seeks a computational research fellow to build mathematical models of the immune system in vivo. These models will be constructed from cutting-edge, high-dimensional, immune-system measurements (e.g., single-cell genomics, chromatin state, proteomics). Our mathematical modeling frameworks span mechanistic (e.g., dynamic gene regulatory networks) to deep learning (e.g., prediction of cellular epigenomes from DNA sequence). Situated at Cincinnati Children's Hospital, we are dedicated to the design of computational methods and systems-immunology studies that will ultimately improve the health of children. Through close collaboration with our physician and experimental colleagues, we iteratively test and refine our models, so that the models yield novel insights into immune-cell function and ultimately guide new therapeutic strategies in the context of autoimmunity, infectious disease and cancer. The ideal candidate will collaborate closely with experimental immunologists, physicians and other computational biologists. The team will design and execute hybrid computational-experimental strategies that push the boundaries of both immunology and computational biology.MAJOR DUTIES AND RESPONSIBILITIES: Design, execute, and record laboratory experiments, and analyze the data. Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department. Present research at laboratory meetings, journal clubs, seminars, and meetings. Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants. Maintain currency in field through continuing education, literature, and seminars. Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures. Perform other duties as assigned.Qualifications - ExternalRequired:Ph.D. in related discipline, MD, or equivalent degreePreferred:The ideal candidate will have a quantitative background in computational/systems biology, engineering, computer science, statistics, math, or a related field. He or she will also (1) be a fluent programmer in at least one language (e.g., Python, R, MATLAB) and be willing to develop fluency in other languages, as needed, (2) have research experience in machine learning, bioinformatics and/or mathematical modeling, and (3) a trackable publication record. An enthusiasm and willingness to develop immunology expertise on the job is also necessary.Primary LocationLocation SScheduleFull timeShiftDay (United States of America)DepartmentImmunobiologyEmployee StatusRegularFTE1Weekly Hours40About UsAt Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's.Cincinnati Children's is: Recognized by U.S. News & World Report as atop 10 best Children's Hospitals in the nation for more than 15 years Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH)Funding Recognized as one of America's Best Large Employers (2025), America's Best Employers for New Grads (2025) One of the nation'sAmerica's Most Innovative Companiesas noted by Fortune Consistently certified as great place to work AApply here:

Created: 2026-01-29