POSTDOCTORAL RESEARCHER - Biochemistry - Nam Lab

A postdoctoral training position is available in the laboratory of in the at UT Southwestern Medical Center to study the mechanisms underlying RNA-protein complexes important for gene regulation. Our laboratory, Nam Lab, works on exciting projects dissecting how chemistry and structure contribute to assembling specific RNA-protein complex architectures important for normal gene expression. More specifically, we investigate the core and regulatory mechanisms that govern RNA processing (e.g., microRNA maturation), modification (e.g., methylation) and folding (e.g., RNA helicases) that impact the RNA function in the cell. To study how proteins and RNAs recognize each other, we use biochemical and biophysical methods. The RNA-protein complexes we study are relevant for normal development as well as diseases. Thus, as we unravel how dysregulated RNA-protein complexes derail gene expression and cause cancer, we use our mechanistic understanding to identify novel therapeutic avenues.Postdoctoral scholars will have many opportunities to learn the newest methods in protein and nucleic acid biochemistry and biophysics, in addition to working in an exciting, fast-evolving field in biomedical sciences. We use various approaches, including cryo-electron microscopy (cryo-EM), X-ray crystallography, molecular biology, nucleic acid and protein biochemistry, genomics with next-generation sequencing, high-throughput screening for small molecule drug discovery, and cancer cell biology. The postdoctoral fellow will have ready access to the top-of-the-line equipment and resources necessary for the above approaches. Candidates must hold a recent M.D. and/or Ph.D. degree. Experience in biochemistry, structural biology, or related discipline, at least one published peer-reviewed journal. ● A summary of your past research experiences and accomplishments. ● A statement of interest in Nam Lab and why you could be a great fit. ● Your goals for your postdoctoral training period. ● Your potential start date. UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis ofrace, color, religion, national origin, sex,sexual orientation, gender identity, gender expression,age, disability, genetic information, citizenship status, or veteran status. This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule. To learn more about the benefits UT Southwestern offers, visit Benefits UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:PPO medical plan, available day one at no cost for full-time employee-only coverage100% coverage for preventive healthcare - no copayPaid Time Off, available day oneRetirement Programs through the Teacher Retirement System of Texas (TRS)Paid Parental Leave BenefitWellness programsTuition ReimbursementPublic Service Loan Forgiveness (PSLF) Qualified Employer

Created: 2026-02-06