Postdoctoral Scientist - Heart Institute - Karlstaedt ...

Job Description Grow your career at Cedars-Sinai Cedars-Sinai Medical Center has been named to the Honor Roll in U.S. News & World Reportu2019s u201cBest Hospitals 2025-2026u201d rankings . When you join our team, youu2019ll have access to groundbreaking biomedical research facilities and world-class medical education programs. We take pride in hiring exceptional, dedicated professionals who are passionate about advancing healthcare. Our physicians, nurses, and staff reflect the culturally and ethnically diverse communities we serve and are united by a shared commitment to excellence. Together, we foster a dynamic, inclusive environment that drives innovation and supports the gold standard of patient care. Are you ready to be a part of breakthrough research? The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and niche care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. The Karlstaedt Lab is looking for a Postdoctoral Fellow to join an ambitious collaborative project to decipher metabolic interactions between cancer cells and the heart. Funded in part by an active NIH/NHLBI grant, this role will involve a close collaboration in a multidisciplinary team together with collaborators within the Smidt Heart Institute and the Cedars Cancer Center. Our research group has an established track record in the study of metabolic pathways using in vivo and ex vivo multi-omics approaches, including computational simulations of cardiac metabolism. We combine ex vivo organ perfusion techniques with stable isotope tracers to measure metabolic flux alterations. The successful candidate will have significant autonomy to develop innovative strategies for projects bridging cardiovascular research and oncology. A unique opportunity within the research group is to establish in vivo mouse models to study metabolic changes in the heart during cancer. Currently, a particular focus is on leukemia and solid tumors (e.g., colorectal cancer). The position will also be connected to a vibrant local scientific community for translational research in Los Angeles. We seek to build on previous expertise and methods devised by our team. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist, our Research Fellow will perform routine and complex laboratory procedures throughout training period and may develop, adapt, and implement new research techniques and protocols. Will analyze and interpret data and may assist in preparation of grant proposals. You will participate in publications and presentations as author or co-author. This position is not responsible for generating grant funds.u2002u2002u2002 Primary Duties and Responsibilities: + May assist in preparation of grant proposals but is not responsible for generating grant funds. + May participate in publications and presentations as author or co-author. + Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. + May develop, adapt, and implement new research techniques and protocols. + Analyzes, interprets, summarizes and compiles data. + Performs routine and complex laboratory procedures throughout training period. + Operates and maintains equipment and instruments. Qualifications Educational Requirements: + Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization is required Experience: + Works independently on research projects designed by a mentor (typically the PI) within area of specialization. + Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. + Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. + Knowledge of safety standards and maintenance of specialized equipment. + Knowledge of mass spectrometry, tracer studies and transgenic mouse models. + Expertise in biological data science and data-driven discovery, scientific programming and omics data analysis, genetics will also be beneficial, as is communicating results in scientific conferences and papers.Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

Created: 2026-03-07