Strategic Business Lead, Product Development, CVRM

The Position Cardiovascular, renal, and metabolic (CVRM) diseases, including obesity and type 2 diabetes, are a major public health emergency, impacting over half of the global population, causing 19 million deaths annually, and imposing a tremendous burden on healthcare systems and society. Roche is uniquely positioned to address these challenges with its comprehensive pipeline of potential best- and first-in-class investigational medicines. The Roche Clinical Development organization is structured by therapeutic area and is responsible for developing and executing the late-stage development (Phase 2-3) clinical strategies and plans to deliver medically differentiated therapies that provide meaningful improvement to patients. We are seeking an accomplished and seasoned leader to drive our portfolio growth. This role requires a unique combination of scientific, business and therapeutic expertise with a proven track record of advancing R&D programs. The CVRM Therapeutic Area (TA) Strategic Business Lead is a newly established position reporting directly to the PDC CVRM TA Head. As a member of the TA Core Leadership Team (LT), you will drive, own, and be accountable for the strategic and operational alignment across key leadership groups within the Roche/Genentech R&D and commercialization ecosystem (for internal audience: including PDC, GPS, PDMA, gRED, and pRED) to support all relevant portfolio business needs. You will focus on building, maintaining, and continuously improving the TA by driving business acumen, operational excellence and fostering community across global sites. Key Responsibilities: Strategic Planning, Strategy Realization & Goal Alignment: + Collaborate with the TA Head and LT to define and set strategic priorities, strategic review cycles, and operational plans; translate Roche/Genentech (PD, PPT) organizational goals into CVRM PDC goals + Direct and Lead the organizational strategy roll out, create robust realization plans and tactics including quantifiable KPIs; own the TA performance dashboard to ensure course correction when goals are at risk + Lead large scale cross-functional projects to ensure the timely and successful delivery of initiatives; develop and manage project plans, track progress, and identify risks and mitigation strategies at the CVRM portfolio level (ie be the u201ckeeperu201d of the various individual project IEPs and to integrate those IEPs on the portfolio level) + Establish and Govern CVRM PDCu2019s engagement model as the primary executive liaison to the broader Roche organization and critical external parties with a focus on community management, team connectivity and cohesion Financial & Resource Management: + Serve as the CVRM TAu2019s Financial Steward with accountability for TA budget allocation; making high-stakes trade-off decisions, identifying cost-saving opportunities and reallocating resources dynamically to high-priority programs to maximize long-term portfolio ROI. + Lead development of measures to manage resources and budgets in collaboration with Finance, People & Culture and Strategic Intelligence & Business Optimization; Partner with people leaders including CVRM LT members to ensure that resource allocation is directly tied to high-impact deliverables and top strategic priorities and ensuring the right talent is on the most critical projects + Monitor resource and budget realization to ensure strict financial responsibility and alignment with TA priorities. + Manage travel guidance and tracking via a centralized travel tracker; manage conference and industry meetings attendance Operational Excellence & Communications: + Bring strong business acumen and leadership to day-to-day CVRM operations; streamline processes and procedures to optimize efficiency and impact; audit existing operational workflows to eliminate redundancies; implement industry-standard benchmarks to measure and improve the

Created: 2026-04-03